| 3134 |
10.1002/hon.2595 |
Managing The Toxicities Of Car T‐Cell Therapy |
Neelapu, Sattva S. |
Hematological Oncology |
2019 |
| 6045 |
10.1016/j.bbmt.2018.12.758 |
Astct Consensus Grading For Cytokine Release Syndrome
And Neurologic Toxicity Associated With Immune Effector Cells |
Lee, Daniel W.; Santomasso, Bianca D.; Locke, Frederick
L., 0000-0001-9063-6691; Ghobadi, Armin, 0000-0001-8848-8474; Turtle,
Cameron J.; Brudno, Jennifer N.; Maus, Marcela V., 0000-0002-7578-0393;
Park, Jae H.; Mead, Elena; Pavletic, Steven; Go, William Y.; Eldjerou,
Lamis; Gardner, Rebecca A.; Frey, Noelle; Curran, Kevin J.; Peggs, Karl;
Pasquini, Marcelo, 0000-0003-1579-2293; Dipersio, John F.; Van Den
Brink, Marcel R.M.; Komanduri, Krishna V.; Grupp, Stephan A.; Neelapu,
Sattva S. |
Biology Of Blood And Marrow Transplantation |
2019 |
| 6046 |
10.1016/j.bbmt.2019.08.003 |
Late Events After Treatment With Cd19-Targeted Chimeric
Antigen Receptor Modified T Cells |
Cordeiro, Ana; Bezerra, Evandro D.; Hirayama, Alexandre
V.; Hill, Joshua A.; Wu, Qian V.; Voutsinas, Jenna; Sorror, Mohamed L.;
Turtle, Cameron J.; Maloney, David G.; Bar, Merav |
Biology Of Blood And Marrow Transplantation |
2020 |
| 6470 |
10.1016/j.blre.2018.11.002 |
Recent Advances In Car T-Cell Toxicity: Mechanisms,
Manifestations And Management |
Brudno, Jennifer N.; Kochenderfer, James N. |
Blood Reviews |
2019 |
| 6773 |
10.1016/j.ccell.2019.02.003 |
Logic-Gated Ror1 Chimeric Antigen Receptor Expression
Rescues T Cell-Mediated Toxicity To Normal Tissues And Enables Selective
Tumor Targeting |
Srivastava, Shivani; Salter, Alexander I.; Liggitt,
Denny; Yechan-Gunja, Sushma; Sarvothama, Megha; Cooper, Kirsten; Smythe,
Kimberly S.; Dudakov, Jarrod A.; Pierce, Robert H.; Rader, Christoph;
Riddell, Stanley R. |
Cancer Cell |
2019 |
| 7464 |
10.1016/j.cell.2018.05.060 |
Single-Cell Map Of Diverse Immune Phenotypes In The
Breast Tumor Microenvironment |
Azizi, Elham; Carr, Ambrose J.; Plitas, George;
Cornish, Andrew E.; Konopacki, Catherine; Prabhakaran, Sandhya; Nainys,
Juozas; Wu, Kenmin; Kiseliovas, Vaidotas; Setty, Manu; Choi, Kristy;
Fromme, Rachel M.; Dao, Phuong; Mckenney, Peter T.; Wasti, Ruby C.;
Kadaveru, Krishna; Mazutis, Linas; Rudensky, Alexander Y.; Pe’Er,
Dana |
Cell |
2018 |
| 7509 |
10.1016/j.cell.2018.09.006 |
A Cancer Cell Program Promotes T Cell Exclusion And
Resistance To Checkpoint Blockade |
Jerby-Arnon, Livnat; Shah, Parin; Cuoco, Michael S.;
Rodman, Christopher; Su, Mei-Ju; Melms, Johannes C.; Leeson, Rachel;
Kanodia, Abhay; Mei, Shaolin; Lin, Jia-Ren; Wang, Shu; Rabasha, Bokang;
Liu, David; Zhang, Gao; Margolais, Claire; Ashenberg, Orr; Ott, Patrick
A.; Buchbinder, Elizabeth I.; Haq, Rizwan; Hodi, F. Stephen; Boland,
Genevieve M.; Sullivan, Ryan J.; Frederick, Dennie T.; Miao, Benchun;
Moll, Tabea; Flaherty, Keith T.; Herlyn, Meenhard; Jenkins, Russell W.;
Thummalapalli, Rohit; Kowalczyk, Monika S.; Canadas, Israel; Schilling,
Bastian; Cartwright, Adam N.R.; Luoma, Adrienne M.; Malu, Shruti; Hwu,
Patrick; Bernatchez, Chantale; Forget, Marie-Andree; Barbie, David A.;
Shalek, Alex K.; Tirosh, Itay; Sorger, Peter K.; Wucherpfennig, Kai; Van
Allen, Eliezer M.; Schadendorf, Dirk; Johnson, Bruce E.; Rotem, Asaf;
Rozenblatt-Rosen, Orit; Garraway, Levi A.; Yoon, Charles H.; Izar,
Benjamin; Regev, Aviv |
Cell |
2018 |
| 7541 |
10.1016/j.cell.2018.10.038 |
Defining T Cell States Associated With Response To
Checkpoint Immunotherapy In Melanoma |
Sade-Feldman, Moshe; Yizhak, Keren; Bjorgaard, Stacey
L.; Ray, John P.; De Boer, Carl G.; Jenkins, Russell W.; Lieb, David J.;
Chen, Jonathan H.; Frederick, Dennie T.; Barzily-Rokni, Michal; Freeman,
Samuel S.; Reuben, Alexandre; Hoover, Paul J.; Villani, Alexandra-Chloe;
Ivanova, Elena; Portell, Andrew; Lizotte, Patrick H.; Aref, Amir R.;
Eliane, Jean-Pierre; Hammond, Marc R.; Vitzthum, Hans; Blackmon, Shauna
M.; Li, Bo; Gopalakrishnan, Vancheswaran; Reddy, Sangeetha M.; Cooper,
Zachary A.; Paweletz, Cloud P.; Barbie, David A.; Stemmer-Rachamimov,
Anat; Flaherty, Keith T.; Wargo, Jennifer A.; Boland, Genevieve M.;
Sullivan, Ryan J.; Getz, Gad; Hacohen, Nir |
Cell |
2018 |
| 7566 |
10.1016/j.cell.2018.11.043 |
Dysfunctional Cd8 T Cells Form A Proliferative,
Dynamically Regulated Compartment Within Human Melanoma |
Li, Hanjie; Van Der Leun, Anne M.; Yofe, Ido; Lubling,
Yaniv; Gelbard-Solodkin, Dikla; Van Akkooi, Alexander C.J.; Van Den
Braber, Marlous; Rozeman, Elisa A.; Haanen, John B.A.G.; Blank,
Christian U.; Horlings, Hugo M.; David, Eyal; Baran, Yael; Bercovich,
Akhiad; Lifshitz, Aviezer; Schumacher, Ton N.; Tanay, Amos; Amit,
Ido |
Cell |
2019 |
| 7865 |
10.1016/j.cell.2020.08.022 |
Single-Cell Analyses Identify Brain Mural Cells
Expressing Cd19 As Potential Off-Tumor Targets For Car-T
Immunotherapies |
Parker, Kevin R., 0000-0001-5532-238X; Migliorini,
Denis; Perkey, Eric, 0000-0003-3275-3181; Yost, Kathryn E.,
0000-0001-6807-950X; Bhaduri, Aparna; Bagga, Puneet,
0000-0002-2264-2341; Haris, Mohammad; Wilson, Neil E.; Liu, Fang;
Gabunia, Khatuna; Scholler, John; Montine, Thomas J.; Bhoj, Vijay G.;
Reddy, Ravinder, 0000-0003-4580-2392; Mohan, Suyash,
0000-0002-4025-115X; Maillard, Ivan; Kriegstein, Arnold R.; June, Carl
H., 0000-0003-0241-3557; Chang, Howard Y.; Posey, Avery D.; Satpathy,
Ansuman T. |
Cell |
2020 |
| 11690 |
10.1016/j.immuni.2018.11.014 |
Checkpoint Blockade Immunotherapy Induces Dynamic
Changes In Pd-1－Cd8+ Tumor-Infiltrating T Cells |
Kurtulus, Sema; Madi, Asaf; Escobar, Giulia; Klapholz,
Max; Nyman, Jackson; Christian, Elena; Pawlak, Mathias; Dionne,
Danielle; Xia, Junrong; Rozenblatt-Rosen, Orit; Kuchroo, Vijay K.;
Regev, Aviv; Anderson, Ana C. |
Immunity |
2019 |
| 11695 |
10.1016/j.immuni.2018.12.021 |
Intratumoral Tcf1+Pd-1+Cd8+ T Cells With Stem-Like
Properties Promote Tumor Control In Response To Vaccination And
Checkpoint Blockade Immunotherapy |
Siddiqui, Imran; Schaeuble, Karin; Chennupati,
Vijaykumar; Fuertes Marraco, Silvia A.; Calderon-Copete, Sandra; Pais
Ferreira, Daniela; Carmona, Santiago J.; Scarpellino, Leonardo; Gfeller,
David; Pradervand, Sylvain; Luther, Sanjiv A.; Speiser, Daniel E.; Held,
Werner |
Immunity |
2019 |
| 11734 |
10.1016/j.immuni.2019.09.013 |
Tcf-1-Centered Transcriptional Network Drives An
Effector Versus Exhausted Cd8 T Cell-Fate Decision |
Chen, Zeyu; Ji, Zhicheng; Ngiow, Shin Foong; Manne,
Sasikanth; Cai, Zhangying; Huang, Alexander C.; Johnson, John; Staupe,
Ryan P.; Bengsch, Bertram; Xu, Caiyue; Yu, Sixiang; Kurachi, Makoto;
Herati, Ramin S.; Vella, Laura A.; Baxter, Amy E.; Wu, Jennifer E.;
Khan, Omar; Beltra, Jean-Christophe; Giles, Josephine R.; Stelekati,
Erietta; Mclane, Laura M.; Lau, Chi Wai; Yang, Xiaolu; Berger, Shelley
L.; Vahedi, Golnaz; Ji, Hongkai; Wherry, E. John |
Immunity |
2019 |
| 11737 |
10.1016/j.immuni.2019.10.009 |
Cd4+ T Cell Help Is Required For The Formation Of A
Cytolytic Cd8+ T Cell Subset That Protects Against Chronic Infection And
Cancer |
Zander, Ryan; Schauder, David; Xin, Gang; Nguyen,
Christine; Wu, Xiaopeng; Zajac, Allan; Cui, Weiguo,
0000-0003-1562-9218 |
Immunity |
2019 |
| 11738 |
10.1016/j.immuni.2019.11.002 |
Proliferating Transitory T Cells With An Effector-Like
Transcriptional Signature Emerge From Pd-1+ Stem-Like Cd8+ T Cells
During Chronic Infection |
Hudson, William H.; Gensheimer, Julia; Hashimoto,
Masao; Wieland, Andreas; Valanparambil, Rajesh M.; Li, Peng; Lin,
Jian-Xin; Konieczny, Bogumila T.; Im, Se Jin; Freeman, Gordon J.;
Leonard, Warren J.; Kissick, Haydn T.; Ahmed, Rafi |
Immunity |
2019 |
| 11752 |
10.1016/j.immuni.2020.04.014 |
Developmental Relationships Of Four Exhausted Cd8+ T
Cell Subsets Reveals Underlying Transcriptional And Epigenetic Landscape
Control Mechanisms |
Beltra, Jean-Christophe; Manne, Sasikanth;
Abdel-Hakeem, Mohamed S.; Kurachi, Makoto; Giles, Josephine R.; Chen,
Zeyu; Casella, Valentina; Ngiow, Shin Foong; Khan, Omar; Huang, Yinghui
Jane; Yan, Patrick; Nzingha, Kito; Xu, Wei; Amaravadi, Ravi K.; Xu,
Xiaowei; Karakousis, Giorgos C.; Mitchell, Tara C.; Schuchter, Lynn M.;
Huang, Alexander C.; Wherry, E. John |
Immunity |
2020 |
| 12101 |
10.1016/j.jacc.2019.10.038 |
Cardiovascular Events Among Adults Treated With
Chimeric Antigen Receptor T-Cells (Car-T) |
Alvi, Raza M.; Frigault, Matthew J.; Fradley, Michael
G.; Jain, Michael D.; Mahmood, Syed S.; Awadalla, Magid; Lee, Dae Hyun;
Zlotoff, Daniel A.; Zhang, Lili; Drobni, Zsofia D.; Hassan, Malek Z.O.;
Bassily, Emmanuel; Rhea, Isaac; Ismail-Khan, Roohi; Mulligan, Connor P.;
Banerji, Dahlia; Lazaryan, Aleksandr; Shah, Bijal D.; Rokicki, Adam;
Raje, Noopur; Chavez, Julio C.; Abramson, Jeremy; Locke, Frederick L.;
Neilan, Tomas G. |
Journal Of The American College Of Cardiology |
2019 |
| 13332 |
10.1016/j.jhep.2019.05.015 |
Tox Promotes The Exhaustion Of Antitumor Cd8+ T Cells
By Preventing Pd1 Degradation In Hepatocellular Carcinoma |
Wang, Xiaochen; He, Qifeng; Shen, Haiyuan; Xia,
Anliang; Tian, Wenfang; Yu, Weiwei; Sun, Beicheng,
0000-0002-3795-4153 |
Journal Of Hepatology |
2019 |
| 18457 |
10.1016/s0140-6736(18)33003-4 |
Oral Ixazomib Maintenance Following Autologous Stem
Cell Transplantation (Tourmaline-Mm3): A Double-Blind, Randomised,
Placebo-Controlled Phase 3 Trial |
Dimopoulos, Meletios A; Gay, Francesca; Schjesvold,
Fredrik; Beksac, Meral; Hajek, Roman; Weisel, Katja Christina;
Goldschmidt, Hartmut; Maisnar, Vladimir; Moreau, Philippe; Min, Chang
Ki; Pluta, Agnieszka; Chng, Wee-Joo; Kaiser, Martin; Zweegman, Sonja;
Mateos, Maria-Victoria; Spencer, Andrew; Iida, Shinsuke; Morgan, Gareth;
Suryanarayan, Kaveri; Teng, Zhaoyang; Skacel, Tomas; Palumbo, Antonio;
Dash, Ajeeta B; Gupta, Neeraj; Labotka, Richard; Rajkumar, S Vincent;
Bar, Daniel; Basso, Alfredo; Fantl, Dorotea; He, Simon; Horvath, Neomi;
Lee, Cindy; Rowlings, Phillip; Taylor, Kerry; Spencer, Andrew; Cochrane,
Tara; Kwok, Fiona; Ramanathan, Sundreswran; Agis, Hermine; Zojer,
Niklas; Kentos, Alain; Offner, Fritz; Van Droogenbroeck, Jan; Wu, Ka
Lung; Maiolino, Angelo; Martinez, Gracia; Zanella, Karla; Capra,
Marcelo; Araujo, Sergio; Gregora, Evzen; Hajek, Roman; Maisnar,
Vladimir; Pour, Ludek; Scudla, Vlastimil; Spicka, Ivan; Abildgaard,
Niels; Andersen, Niels; Jensen, Bo Amdi; Helleberg, Carsten; Plesner,
Torben; Salomo, Morten; Svirskaite, Asta; Delarue, Richard; Moreau,
Philippe; Blau, Igor; Goldschmidt, Hartmut; Schieferdecker, Aneta;
Teleanu, Veronica; Munder, Markus; Rollig, Christoph; Salwender,
Han-Juergen; Fuhrmann, Stephan; Weisel, Katja; Duerig, Jan; Zeis,
Matthias; Klein, Stefan; Reimer, Peter; Schmidt, Christian; Scheid,
Christof; Mayer, Karin; Hoffmann, Martin; Sosada, Markus; Dimopoulos,
Athanasios; Delimpasi, Sosana; Kyrtsonis, Mary-Christine;
Anagnostopoulos, Achilleas; Nagy, Zsolt; Illes, Arpad; Egyed, Miklos;
Borbenyi, Zita; Mikala, Gabor; Dally, Najib; Horowitz, Netanel; Gutwein,
Odit; Nemets, Anatoly; Vaxman, Iuliana; Shvetz, Olga; Trestman,
Svetlana; Ruchlemer, Rosa; Nagler, Arnon; Tadmor, Tamar; Rouvio, Ory;
Preis, Meir; Gay, Francesca; Cavo, Michele; De Rosa, Luca; Musto,
Pellegrino; Cafro, Anna; Tosi, Patrizia; Offidani, Massimo; Corso,
Alessandro; Rossi, Giuseppe; Liberati, Anna Marina; Bosi, Alberto;
Suzuki, Kenshi; Iida, Shinsuke; Nakaseko, Chiaki; Ishikawa, Takayuki;
Matsumoto, Morio; Nagai, Hirokazu; Sunami, Kazutaka; Chou, Takaaki;
Akashi, Koichi; Takezako, Naoki; Hagiwara, Shotaro; Eom, Hyeon Seok; Jo,
Deog-Yeon; Kim, Jin Seok; Lee, Jae Hoon; Min, Chang Ki; Yoon, Sung Soo;
Yoon, Dok Hyun; Kim, Kihyun; Zweegman, Sonja; Levin, Mark-David;
Vellenga, Edo; Minnema, Monique; Schjesvold, Fredrik; Waage, Anders;
Haukas, Einar; Grosicki, Sebastian; Pluta, Andrzej; Robak, Tadeusz;
Marques, Herlander; Bergantim, Rui; Campilho, Fernando; Chng, Wee Joo;
Goh, Yeow Tee; Mcdonald, Andrew; Rapoport, Bernado; Alvarez Rivas,
Miguel Angel; De Arriba De La Fuente, Felipe; Gonzalez Montes, Yolanda;
Martin Sanchez, Jesus; Mateos, Maria Victoria; Oriol Rocafiguera,
Albert; Rosinol, Laura; San Miguel, Jesus; Perez De Oteyza, Jaime;
Encinas, Cristina; Alegre-Amor, Adrian; Lopez-Guia, Ana; Axelsson, Per;
Carlson, Kristina; Stromberg, Olga; Hansson, Markus; Hveding Blimark,
Cecile; Mueller, Rouven; Chen, Chih-Cheng; Liu, Ta-Chih; Huang,
Shang-Yi; Wang, Po-Nan; Na Nakorn, Thanyaphong; Prayongratana, Kannadit;
Beksac, Meral; Unal, Ali; Goker, Hakan; Sonmez, Mehmet; Korenkova,
Sybiryna; Chaidos, Aristeidis; Oakervee, Heather; Sati, Hamdi; Benjamin,
Reuben; Wechalekar, Ashutosh; Garg, Mamta; Kaiser, Martin; Ramasamy,
Karthik; Cook, Gordon; Chantry, Andrew; Jenner, Matthew; Buadi, Francis;
Berryman, Robert; Janakiram, Murali |
The Lancet |
2019 |
| 18515 |
10.1016/s0140-6736(19)31240-1 |
Bortezomib, Thalidomide, And Dexamethasone With Or
Without Daratumumab Before And After Autologous Stem-Cell
Transplantation For Newly Diagnosed Multiple Myeloma (Cassiopeia): A
Randomised, Open-Label, Phase 3 Study |
Moreau, Philippe; Attal, Michel; Hulin, Cyrille;
Arnulf, Bertrand; Belhadj, Karim; Benboubker, Lotfi; Bene, Marie C;
Broijl, Annemiek; Caillon, Helene; Caillot, Denis; Corre, Jill;
Delforge, Michel; Dejoie, Thomas; Doyen, Chantal; Facon, Thierry;
Sonntag, Cecile; Fontan, Jean; Garderet, Laurent; Jie, Kon-Siong;
Karlin, Lionel; Kuhnowski, Frederique; Lambert, Jerome; Leleu, Xavier;
Lenain, Pascal; Macro, Margaret; Mathiot, Claire; Orsini-Piocelle,
Frederique; Perrot, Aurore; Stoppa, Anne-Marie; Van De Donk, Niels Wcj;
Wuilleme, Soraya; Zweegman, Sonja; Kolb, Brigitte; Touzeau, Cyrille;
Roussel, Murielle; Tiab, Mourad; Marolleau, Jean-Pierre; Meuleman,
Nathalie; Vekemans, Marie-Christiane; Westerman, Matthijs; Klein, Saskia
K; Levin, Mark-David; Fermand, Jean Paul; Escoffre-Barbe, Martine;
Eveillard, Jean-Richard; Garidi, Reda; Ahmadi, Tahamtan; Zhuang, Sen;
Chiu, Christopher; Pei, Lixia; De Boer, Carla; Smith, Elena; Deraedt,
William; Kampfenkel, Tobias; Schecter, Jordan; Vermeulen, Jessica;
Avet-Loiseau, Herve; Sonneveld, Pieter |
The Lancet |
2019 |
| 18573 |
10.1016/s0140-6736(19)32556-5 |
Isatuximab Plus Pomalidomide And Low-Dose Dexamethasone
Versus Pomalidomide And Low-Dose Dexamethasone In Patients With Relapsed
And Refractory Multiple Myeloma (Icaria-Mm): A Randomised, Multicentre,
Open-Label, Phase 3 Study |
Attal, Michel; Richardson, Paul G; Rajkumar, S Vincent;
San-Miguel, Jesus; Beksac, Meral; Spicka, Ivan; Leleu, Xavier;
Schjesvold, Fredrik; Moreau, Philippe; Dimopoulos, Meletios A; Huang,
Jeffrey Shang-Yi; Minarik, Jiri; Cavo, Michele; Prince, H Miles; Mace,
Sandrine; Corzo, Kathryn P; Campana, Frank; Le-Guennec, Solenn; Dubin,
Franck; Anderson, Kenneth C; Attal, Michel; Richardson, Paul G.;
Rajkumar, Vincent; San-Miguel, Jesus; Beksac, Meral; Spicka, Ivan;
Leleu, Xavier; Schjesvold, Fredrik; Moreau, Philippe; Dimopoulos,
Meletios A.; Huang, Jeffrey Shang-Yi; Minarik, Jiri; Cavo, Michele;
Prince, H. Miles; Mace, Sandrine; Corzo, Kathryn P.; Campana, Frank;
Le-Guennec, Solenn; Dubin, Franck; Anderson, Kenneth C.; Harrison,
Simon; Janowski, Wojt; Kerridge, Ian; Spencer, Andrew; Delforge, Michel;
Fostier, Karel; Vlummens, Philip; Wu, Ka Lung; Leblanc, Richard; Pavic,
Michel; Sebag, Michael; Hajek, Roman; Maisnar, Vladimir; Pour, Ludek;
Gregersen, Henrik; Benbouker, Lotfi; Caillot, Denis; Escoffre-Barbe,
Martine; Facon, Thierry; Frenzel, Laurent; Hulin, Cyrille; Karlin,
Lionel; Kolb, Brigitte; Pegourie, Brigitte; Perrot, Aurore; Tiab,
Mourad; Vincent, Laure; Niederwieser, Dietger; Anagnostopoulos,
Achilles; Delimpasi, Sosana; Kyrtsonis, Marie-Christine; Symeonidis,
Anargyros; Illes, Arpad; Mikala, Gabor; Nagy, Zsolt; Bringen, Sara;
Corradini, Paolo; Fabio, Ciceri; Lemoli, Roberto; Liberati, Anna;
Nozzoli, Chiara; Zambello, Renato; Iida, Shinsuke; Ikeda, Takashi;
Iyama, Satoshi; Matsumoto, Morio; Shimazaki, Chihiro; Sunami, Kazutaka;
Suzuki, Kenshi; Uchiyama, Michihiro; Koh, Youngil; Kim, Kihyun; Lee, Jae
Hoon; Min, Chang-Ki; Blacklock, Hillary; Goodman, Hugh; Neylon, Annette;
Simpson, David; Grosicki, Sebastian; Jurczyszyn, Artur; Walter-Croneck,
Adam; Warzocha, Krzysztof; Araujo, Luis; Moreira, Claudia; Doronin,
Vadim; Mendeleeva, Larisa; Vorobyev, Vladimir; Vranovsky, Andrej;
Alegre, Adrian; Gironella, Mercedes; Gonzalez Perez, Marta Sonia;
Montes, Carmen; Ocio, Enrique; Rodriguez, Paula; Hardling, Mats; Lauri,
Birgitta; Wang, Ming-Chung; Yeh, Su-Peng; Arat, Mutlu; Demirkan, Fatih;
Gulbas, Zafer; Besisik, Sevgi Kalayoglu; Karadogan, Ihsan; Tuglular,
Tulin; Unal, Ali; Vural, Filiz; Sive, Jonathan; Streetly, Matthew; Yong,
Kwee; Tache, Jason |
The Lancet |
2019 |
| 18580 |
10.1016/s0140-6736(19)32956-3 |
Overall Survival With Daratumumab, Bortezomib,
Melphalan, And Prednisone In Newly Diagnosed Multiple Myeloma (Alcyone):
A Randomised, Open-Label, Phase 3 Trial |
Mateos, Maria-Victoria; Cavo, Michele; Blade, Joan;
Dimopoulos, Meletios A; Suzuki, Kenshi; Jakubowiak, Andrzej; Knop,
Stefan; Doyen, Chantal; Lucio, Paulo; Nagy, Zsolt; Pour, Ludek; Cook,
Mark; Grosicki, Sebastian; Crepaldi, Andre; Liberati, Anna Marina;
Campbell, Philip; Shelekhova, Tatiana; Yoon, Sung-Soo; Iosava, Genadi;
Fujisaki, Tomoaki; Garg, Mamta; Krevvata, Maria; Chen, Ying; Wang,
Jianping; Kudva, Anupa; Ukropec, Jon; Wroblewski, Susan; Qi, Ming;
Kobos, Rachel; San-Miguel, Jesus |
The Lancet |
2020 |
| 18665 |
10.1016/s0140-6736(20)30734-0 |
Carfilzomib, Dexamethasone, And Daratumumab Versus
Carfilzomib And Dexamethasone For Patients With Relapsed Or Refractory
Multiple Myeloma (Candor): Results From A Randomised, Multicentre,
Open-Label, Phase 3 Study |
Dimopoulos, Meletios; Quach, Hang; Mateos,
Maria-Victoria; Landgren, Ola; Leleu, Xavier; Siegel, David; Weisel,
Katja; Yang, Hui; Klippel, Zandra; Zahlten-Kumeli, Anita; Usmani, Saad
Z |
The Lancet |
2020 |
| 18742 |
10.1016/s0140-6736(20)31366-0 |
Lisocabtagene Maraleucel For Patients With Relapsed Or
Refractory Large B-Cell Lymphomas (Transcend Nhl 001): A Multicentre
Seamless Design Study |
Abramson, Jeremy S; Palomba, M Lia; Gordon, Leo I;
Lunning, Matthew A; Wang, Michael; Arnason, Jon; Mehta, Amitkumar;
Purev, Enkhtsetseg; Maloney, David G; Andreadis, Charalambos; Sehgal,
Alison; Solomon, Scott R; Ghosh, Nilanjan; Albertson, Tina M; Garcia,
Jacob; Kostic, Ana; Mallaney, Mary; Ogasawara, Ken; Newhall, Kathryn;
Kim, Yeonhee; Li, Daniel; Siddiqi, Tanya |
The Lancet |
2020 |
| 18830 |
10.1016/s1470-2045(18)30576-x |
Targeting B-Cell Maturation Antigen With Gsk2857916
Antibody<U+2013>Drug Conjugate In Relapsed Or Refractory Multiple
Myeloma (Bma117159): A Dose Escalation And Expansion Phase 1 Trial |
Trudel, Suzanne; Lendvai, Nikoletta; Popat, Rakesh;
Voorhees, Peter M; Reeves, Brandi; Libby, Edward N; Richardson, Paul G;
Anderson, Larry D; Sutherland, Heather J; Yong, Kwee; Hoos, Axel;
Gorczyca, Michele M; Lahiri, Soumi; He, Zangdong; Austin, Daren J;
Opalinska, Joanna B; Cohen, Adam D |
The Lancet Oncology |
2018 |
| 18838 |
10.1016/s1470-2045(18)30687-9 |
Lenalidomide Maintenance Versus Observation For
Patients With Newly Diagnosed Multiple Myeloma (Myeloma Xi): A
Multicentre, Open-Label, Randomised, Phase 3 Trial |
Jackson, Graham H; Davies, Faith E; Pawlyn, Charlotte;
Cairns, David A; Striha, Alina; Collett, Corinne; Hockaday, Anna; Jones,
John R; Kishore, Bhuvan; Garg, Mamta; Williams, Cathy D; Karunanithi,
Kamaraj; Lindsay, Jindriska; Jenner, Matthew W; Cook, Gordon; Russell,
Nigel H; Kaiser, Martin F; Drayson, Mark T; Owen, Roger G; Gregory,
Walter M; Morgan, Gareth J |
The Lancet Oncology |
2019 |
| 18856 |
10.1016/s1470-2045(18)30864-7 |
Long-Term Safety And Activity Of Axicabtagene
Ciloleucel In Refractory Large B-Cell Lymphoma (Zuma-1): A Single-Arm,
Multicentre, Phase 1<U+2013>2 Trial |
Locke, Frederick L; Ghobadi, Armin; Jacobson, Caron A;
Miklos, David B; Lekakis, Lazaros J; Oluwole, Olalekan O; Lin, Yi;
Braunschweig, Ira; Hill, Brian T; Timmerman, John M; Deol, Abhinav;
Reagan, Patrick M; Stiff, Patrick; Flinn, Ian W; Farooq, Umar; Goy,
Andre; Mcsweeney, Peter A; Munoz, Javier; Siddiqi, Tanya; Chavez, Julio
C; Herrera, Alex F; Bartlett, Nancy L; Wiezorek, Jeffrey S; Navale,
Lynn; Xue, Allen; Jiang, Yizhou; Bot, Adrian; Rossi, John M; Kim, Jenny
J; Go, William Y; Neelapu, Sattva S |
The Lancet Oncology |
2019 |
| 18876 |
10.1016/s1470-2045(19)30152-4 |
Pomalidomide, Bortezomib, And Dexamethasone For
Patients With Relapsed Or Refractory Multiple Myeloma Previously Treated
With Lenalidomide (Optimismm): A Randomised, Open-Label, Phase 3
Trial |
Richardson, Paul G; Oriol, Albert; Beksac, Meral;
Liberati, Anna Marina; Galli, Monica; Schjesvold, Fredrik; Lindsay,
Jindriska; Weisel, Katja; White, Darrell; Facon, Thierry; San Miguel,
Jesus; Sunami, Kazutaka; O’Gorman, Peter; Sonneveld, Pieter; Robak,
Pawel; Semochkin, Sergey; Schey, Steve; Yu, Xin; Doerr, Thomas;
Bensmaine, Amine; Biyukov, Tsvetan; Peluso, Teresa; Zaki, Mohamed;
Anderson, Kenneth; Dimopoulos, Meletios; Abildgaard, Niels; Adler,
Howard; Altuntas, Fevzi; Akay, Olga Meltem; Amin, Bipinkumar;
Anagnostopoulos, Achilleas; Anderson, Larry; Anttila, Pekka; Araujo,
Carla; Arce-Lara, Carlos; Aydin, Yildiz; Basu, Supratik; Battini,
Ramakrishna; Beeker, Thaddeus; Benboubker, Lotfi; Ben-Yehuda, Dina;
Blade, Joan; Blau, Igor Wolfgang; Boccia, Ralph; Burke, Lillian; Byeff,
Peter; Cascavilla, Nicola; Cavo, Michele; Chantry, Andrew; Charles, Yen;
Chaudhry, Arvind; Corso, Alessandro; Coyne, Mark; De Arriba, Felipe;
Delimpasi, Sosana; Desjardins, Pierre; Dhakal, Binod; Di Bartolomeo,
Paolo; Di Raimondo, Francesco; Durig, Jan; Engelhardt, Monika;
Escoffre-Barbe, Martine; Esteves, Graca; Flogegard, Max; Gabrail,
Nashat; Gamberi, Barbara; Garrison, Mitchell; Gay, Julie; Gisslinger,
Heinz; Goldschmidt, Hartmut; Goncalves, Cristina; Gressot, Laurent;
Grosicki, Sebastian; Hanna, Wahid; Hayden, Patrick; Henriques Bernardo,
Maria Manuela; Hermann, Robert; Holden, Viran; Honkalehto, Kirsti;
Huben, Marianne; Huffman, John; Hunter, Hannah; Hus, Marek; Jagasia,
Madan; Jagganath, Sundar; Janakiram, Murali; Jaiyesimi, Ishmael; Jenner,
Matthew; Joao, Cristina; Johnson, Peter; Jurcyszyn, Artur;
Kalayo<U+011F>lu Be<U+015F>i<U+015F>ik, Sevgi;
Kambhampati, Suman; Kanate, Abraham; Karado<U+011F>an, Ihsan;
Khojasteh, Ali; Kirkel, Dean; Komarnicki, Mieczyslaw; Krauth,
Maria-Theresa; Kuriakose, Phillip; Larocca, Alessandra; Lauri, Birgitta;
Leleu, Xavier; Lucio, Paulo; Luppi, Mario; Mangiacavalli, Silvia;
Mariette, Clara; Matsue, Kosei; Mellqvist, Ulf-Henri; Mendeleeva,
Larisa; Meshad, Michael; Miller, Carole; Mohrbacher, Ann; Moreau,
Philippe; Morelli, Anna Maria; Muldur, Ercan; Naassan, Anthony; Nahi,
Hareth; Nair, Rajesh; O’Dwyer, Mike; Ongoren Aydin, Seniz; Openshaw,
Thomas; O’Rourke, Timothy; Osswald, Michael; Overton, Lindsay; Pati,
Asmin; Pavic, Michel; Pegourie, Brigitte; Pehlivan, Mustafa; Pierola,
Ana Alfonso; Plesner, Torben; Pluta, Andrzej; Rabin, Neil; Ramasamy,
Karthik; Rambaldi, Alessandro; Rodriguez, Paula; Rollig, Christoph;
Rosenblatt, Jacalyn; Rosenbluth, Jonathan; Salomo, Morten; Samoylova,
Olga; Sastre Moral, Jose; Sati, Hamdi; Selleri, Carmine; Shafeek, Salim;
Shinagawa, Atsushi; Sleckman, Bethany; Smith, Clay; Sonmez, Mehmet;
Stone, Chester; Streetly, Matthew; Suzuki, Kenshi; Taetle, Raymond;
Tafuri, Agostino; Takezako, Naoki; Teke, Hava Uskudar; Vapaatalo, Mirja;
Vassilopoulos, George; Verma, Amit; Vidito, Sarah; Viterbo, Luisa;
Vural, Filiz; Wang, Xiang Sean; Ya<U+011F>ci, Munci; Yee,
Andrew |
The Lancet Oncology |
2019 |
| 18915 |
10.1016/s1470-2045(19)30788-0 |
Belantamab Mafodotin For Relapsed Or Refractory
Multiple Myeloma (Dreamm-2): A Two-Arm, Randomised, Open-Label, Phase 2
Study |
Lonial, Sagar; Lee, Hans C; Badros, Ashraf; Trudel,
Suzanne; Nooka, Ajay K; Chari, Ajai; Abdallah, Al-Ola; Callander,
Natalie; Lendvai, Nikoletta; Sborov, Douglas; Suvannasankha, Attaya;
Weisel, Katja; Karlin, Lionel; Libby, Edward; Arnulf, Bertrand; Facon,
Thierry; Hulin, Cyrille; Kortum, K Martin; Rodriguez-Otero, Paula;
Usmani, Saad Z; Hari, Parameswaran; Baz, Rachid; Quach, Hang; Moreau,
Philippe; Voorhees, Peter M; Gupta, Ira; Hoos, Axel; Zhi, Eric; Baron,
January; Piontek, Trisha; Lewis, Eric; Jewell, Roxanne C; Dettman,
Elisha J; Popat, Rakesh; Esposti, Simona Degli; Opalinska, Joanna;
Richardson, Paul; Cohen, Adam D |
The Lancet Oncology |
2020 |
| 18933 |
10.1016/s1470-2045(20)30225-4 |
Tafasitamab Plus Lenalidomide In Relapsed Or Refractory
Diffuse Large B-Cell Lymphoma (L-Mind): A Multicentre, Prospective,
Single-Arm, Phase 2 Study |
Salles, Gilles; Duell, Johannes; Gonzalez Barca, Eva;
Tournilhac, Olivier; Jurczak, Wojciech; Liberati, Anna Marina; Nagy,
Zsolt; Obr, Ale<U+0161>; Gaidano, Gianluca; Andre, Marc;
Kalakonda, Nagesh; Dreyling, Martin; Weirather, Johannes;
Dirnberger-Hertweck, Maren; Ambarkhane, Sumeet; Fingerle-Rowson, Gunter;
Maddocks, Kami |
The Lancet Oncology |
2020 |
| 19377 |
10.1016/s2352-3026(19)30026-2 |
Polatuzumab Vedotin Or Pinatuzumab Vedotin Plus
Rituximab In Patients With Relapsed Or Refractory Non-Hodgkin Lymphoma:
Final Results From A Phase 2 Randomised Study (Romulus) |
Morschhauser, Franck; Flinn, Ian W; Advani, Ranjana;
Sehn, Laurie H; Diefenbach, Catherine; Kolibaba, Kathryn; Press, Oliver
W; Salles, Gilles; Tilly, Herve; Chen, Andy I; Assouline, Sarit; Cheson,
Bruce D; Dreyling, Martin; Hagenbeek, Anton; Zinzani, Pier Luigi; Jones,
Surai; Cheng, Ji; Lu, Dan; Penuel, Elicia; Hirata, Jamie; Wenger,
Michael; Chu, Yu-Waye; Sharman, Jeff |
The Lancet Haematology |
2019 |
| 19379 |
10.1016/s2352-3026(19)30109-7 |
Pembrolizumab Plus Lenalidomide And Dexamethasone For
Patients With Treatment-Naive Multiple Myeloma (Keynote-185): A
Randomised, Open-Label, Phase 3 Trial |
Usmani, Saad Zafar; Schjesvold, Fredrik; Oriol, Albert;
Karlin, Lionel; Cavo, Michele; Rifkin, Robert M; Yimer, Habte Aragaw;
Leblanc, Richard; Takezako, Naoki; Mccroskey, Robert Donald; Lim, Andrew
Boon Ming; Suzuki, Kenshi; Kosugi, Hiroshi; Grigoriadis, George; Avivi,
Irit; Facon, Thierry; Jagannath, Sundar; Lonial, Sagar; Ghori, Razi
Uddin; Farooqui, Mohammed Z H; Marinello, Patricia; San-Miguel, Jesus;
Lim, Andrew; Grigoriadis, George; Walker, Trish; Nicol, Andrew; Leblanc,
Richard; Reece, Donna; Elemary, Mohamed; Boudreault Pedneault, Jean
Samuel; Karlin, Lionel; Facon, Thierry; Attal, Michel; Weisel, Katja;
Engelhardt, Monika; Mackensen, Andreas; Quinn, John; Avivi, Irit; Cohen,
Amos; Magen-Nativ, Hila; Benyamini, Noam; Cavo, Michele; Larocca,
Alessandra; Takezako, Naoki; Suzuki, Kenshi; Kosugi, Hiroshi; Matsumoto,
Morio; Iida, Shinsuke; Ishikawa, Takayuki; Kondo, Yukio; Sunami,
Kazutaka; Ando, Kiyoshi; Teshima, Takanori; Chou, Takaaki; Iwasaki,
Hiromi; Miki, Hirokazu; Matsumura, Itaru; Onishi, Yasushi; Izutsu, Koji;
Kizaki, Masahiro; George, Anupkumar; Blacklock, Hillary; Simpson, David;
Schjesvold, Fredrik; Waage, Anders; Samoilova, Olga; Nikitin, Evgeniy;
Chagorova, Tatiana; Mcdonald, Andrew; Patel, Moosa; Oriol Rocafiguera,
Albert; San Miguel Izquierdo, Jesus; Mateos, Maria; Streetly, Matthew;
Forsyth, Peter; Jackson, Graham; Jenkins, Stephen; Rifkin, Robert;
Yimer, Habte; Mccroskey, Robert; Martincic, Danko; Tarantolo, Stefano;
Larson, Sarah; Faroun, Yacoub; Vaughn, Jennifer; Baz, Rachid; Saylors,
Gene; Neppalli, Amarendra; Raptis, Anastasios; Fung, Henry; Janosky,
Maxwell; Stevens, Don; Coleman, Morton; Costa, Dennis; Cross, Scott;
Fanning, Suzanne; Berges, Daniel Farray; Harris, Thomas; Zackon, Ira;
Atanackovic, Djordje; Lee, Kelvin; Oliff, Ira; Lee, Wes; Bensinger,
William; Lutzky, Jose; Baron, Ari; Hayek, Fadi; Kirschner, Eli; Bharany,
Neeraj; Overton, Lindsay; Mannem, Siva; Harroff, Allyson; Jain, Sharad;
Roque, Tammy; Mcintyre, Kristi; Yasencha, Christopher K; Houck,
William |
The Lancet Haematology |
2019 |
| 19380 |
10.1016/s2352-3026(19)30110-3 |
Pembrolizumab Plus Pomalidomide And Dexamethasone For
Patients With Relapsed Or Refractory Multiple Myeloma (Keynote-183): A
Randomised, Open-Label, Phase 3 Trial |
Mateos, Maria-Victoria; Blacklock, Hilary; Schjesvold,
Fredrik; Oriol, Albert; Simpson, David; George, Anupkumar; Goldschmidt,
Hartmut; Larocca, Alessandra; Chanan-Khan, Asher; Sherbenou, Daniel;
Avivi, Irit; Benyamini, Noam; Iida, Shinsuke; Matsumoto, Morio; Suzuki,
Kenshi; Ribrag, Vincent; Usmani, Saad Z; Jagannath, Sundar; Ocio,
Enrique M; Rodriguez-Otero, Paula; San Miguel, Jesus; Kher, Uma;
Farooqui, Mohammed; Liao, Jason; Marinello, Patricia; Lonial, Sagar;
Nicol, Andrew; Grigoriadis, George; Catalano, John; Leblanc, Richard;
Elemary, Mohamed; Bahlis, Nizar; Facon, Thierry; Karlin, Lionel; Ribrag,
Vincent; Attal, Michel; Goldschmidt, Hartmut; Engelhardt, Monika;
Weisel, Katja; Mackensen, Andreas; Nagler, Arnon; Ben Yehuda, Dina;
Avivi, Irit; Benyamini, Noam; Magen-Nativ, Hila; Palumbo, Antonio; Cavo,
Michele; Tobinai, Kensei; Iida, Shinsuke; Chou, Takaai; Suzuki, Kenshi;
Kosugi, Hiroshi; Taniwaki, Masafumi; Sunami, Kazutaka; Matsumoto, Morio;
Ando, Kiyoshi; Ganly, Peter; Blacklock, Hilary; Simpson, David; George,
Anupkumar; Schjesvold, Fredrik; Gjertsen, Bjorn; Lahuerta, Juan; Blade,
Joan; Oriol Rocafiguera, Albert; Mateos, Maria; Rodriguez-Otero, Paula;
Larson, Sarah; Atanackovic, Djordje; Devarakonda, Srinivas; Bitran,
Jacob; Zonder, Jeffrey; Morganstein, Neil; Hay, Mohammad; Chanan-Khan,
Asher; Saylors, Gene; Kio, Ebenezer; Oliff, Ira; Kirkel, Dean;
Shtivelband, Mikhail; Yuen, Carrie; Yee, Andrew; Shah, Jatin; Htut, Myo;
Raza, Shahzad; Chhabra, Saurabh; Stiff, Patrick; Hari, Parameswaran;
Bank, Bruce; Malek, Ehsan; Gasparetto, Cristina; Faroun, Ycaoub;
Sherbenou, Daniel; Kreisle, William; Singhal, Seema; Rosenblatt,
Jacalyn; Usmani, Saad; Lee, Wes; Safah, Hana; Lutzky, Jose; Suh, Jason;
Pan, Dorothy; Baron, Ari; Manges, Robert; Steis, Ronald; Oliveira,
Moacyr; Moreb, Jan; Callander, Natalie; Anz, Bertrand; Raptis,
Anastasios; Stampleman, Laura; Melear, Jason; Boyd, Thomas; Garbo,
Lawrence; Klein, Leonard; Shao, Spencer; Lyons, Roger; Mcintyre, Kristi;
Tarantolo, Stefano; Yasenchak, Christopher; Yimer, Habte |
The Lancet Haematology |
2019 |
| 19381 |
10.1016/s2352-3026(19)30115-2 |
A Combination Of Humanised Anti-Cd19 And Anti-Bcma Car
T Cells In Patients With Relapsed Or Refractory Multiple Myeloma: A
Single-Arm, Phase 2 Trial |
Yan, Zhiling; Cao, Jiang; Cheng, Hai; Qiao, Jianlin;
Zhang, Huanxin; Wang, Ying; Shi, Ming; Lan, Jianping; Fei, Xiaoming;
Jin, Lai; Jing, Guangjun; Sang, Wei; Zhu, Feng; Chen, Wei; Wu, Qingyun;
Yao, Yao; Wang, Gang; Zhao, Jing; Zheng, Junnian; Li, Zhenyu; Xu,
Kailin |
The Lancet Haematology |
2019 |
| 19385 |
10.1016/s2352-3026(20)30099-5 |
Autologous Haematopoietic Stem-Cell Transplantation
Versus Bortezomib<U+2013>Melphalan<U+2013>Prednisone, With
Or Without
Bortezomib<U+2013>Lenalidomide<U+2013>Dexamethasone
Consolidation Therapy, And Lenalidomide Maintenance For Newly Diagnosed
Multiple Myeloma (Emn02/Ho95): A Multicentre, Randomised, Open-Label,
Phase 3 Study |
Cavo, Michele; Gay, Francesca; Beksac, Meral; Pantani,
Lucia; Petrucci, Maria Teresa; Dimopoulos, Meletios A; Dozza, Luca; Van
Der Holt, Bronno; Zweegman, Sonja; Oliva, Stefania; Van Der Velden,
Vincent H J; Zamagni, Elena; Palumbo, Giuseppe A; Patriarca, Francesca;
Montefusco, Vittorio; Galli, Monica; Maisnar, Vladimir; Gamberi,
Barbara; Hansson, Markus; Belotti, Angelo; Pour, Ludek; Ypma, Paula;
Grasso, Mariella; Croockewit, Alexsandra; Ballanti, Stelvio; Offidani,
Massimo; Vincelli, Iolanda D; Zambello, Renato; Liberati, Anna Marina;
Andersen, Niels Frost; Broijl, Annemiek; Troia, Rossella; Pascarella,
Anna; Benevolo, Giulia; Levin, Mark-David; Bos, Gerard; Ludwig, Heinz;
Aquino, Sara; Morelli, Anna Maria; Wu, Ka Lung; Boersma, Rinske; Hajek,
Roman; Durian, Marc; Von Dem Borne, Peter A; Caravita Di Toritto,
Tommaso; Zander, Thilo; Driessen, Christoph; Specchia, Giorgina; Waage,
Anders; Gimsing, Peter; Mellqvist, Ulf-Henrik; Van Marwijk Kooy,
Marinus; Minnema, Monique; Mandigers, Caroline; Cafro, Anna Maria;
Palmas, Angelo; Carvalho, Susanna; Spencer, Andrew; Boccadoro, Mario;
Sonneveld, Pieter |
The Lancet Haematology |
2020 |
| 22175 |
10.1038/s41375-019-0435-7 |
Outcomes Of Patients With Multiple Myeloma Refractory
To Cd38-Targeted Monoclonal Antibody Therapy |
Gandhi, Ujjawal H.; Cornell, Robert F.; Lakshman,
Arjun; Gahvari, Zhubin J.; Mcgehee, Elizabeth; Jagosky, Megan H.; Gupta,
Ridhi; Varnado, William; Fiala, Mark A.; Chhabra, Saurabh; Malek, Ehsan;
Mansour, Joshua; Paul, Barry; Barnstead, Alyssa; Kodali, Saranya;
Neppalli, Amarendra; Liedtke, Michaela; Narayana, Swapna; Godby, Kelly
N.; Kang, Yubin; Kansagra, Ankit, 0000-0001-6901-0782; Umyarova, Elvira;
Scott, Emma C.; Hari, Parameswaran; Vij, Ravi; Usmani, Saad Z.;
Callander, Natalie S.; Kumar, Shaji K., 0000-0001-5392-9284; Costa,
Luciano J., 0000-0001-5362-2469 |
Leukemia |
2019 |
| 22180 |
10.1038/s41375-020-0734-z |
B-Cell Maturation Antigen (Bcma) In Multiple Myeloma:
Rationale For Targeting And Current Therapeutic Approaches |
Shah, Nina; Chari, Ajai; Scott, Emma; Mezzi, Khalid;
Usmani, Saad Z. |
Leukemia |
2020 |
| 22347 |
10.1038/s41408-019-0196-6 |
Antibody<U+2013>Drug Conjugate, Gsk2857916, In
Relapsed/Refractory Multiple Myeloma: An Update On Safety And Efficacy
From Dose Expansion Phase I Study |
Trudel, Suzanne; Lendvai, Nikoletta; Popat, Rakesh;
Voorhees, Peter M.; Reeves, Brandi; Libby, Edward N.; Richardson, Paul
G.; Hoos, Axel; Gupta, Ira; Bragulat, Veronique; He, Zangdong;
Opalinska, Joanna B.; Cohen, Adam D. |
Blood Cancer Journal |
2019 |
| 22349 |
10.1038/s41409-019-0487-3 |
Early And Late Hematologic Toxicity Following Cd19
Car-T Cells |
Fried, Shalev; Avigdor, Abraham; Bielorai, Bella; Meir,
Amilia; Besser, Michal J.; Schachter, Jacob; Shimoni, Avichai; Nagler,
Arnon; Toren, Amos; Jacoby, Elad, 0000-0003-1411-8942 |
Bone Marrow Transplantation |
2019 |
| 22544 |
10.1038/s41467-018-05072-0 |
Co-Expression Of Cd39 And Cd103 Identifies
Tumor-Reactive Cd8 T Cells In Human Solid Tumors |
Duhen, Thomas; Duhen, Rebekka; Montler, Ryan; Moses,
Jake; Moudgil, Tarsem; De Miranda, Noel F.; Goodall, Cheri P.; Blair,
Tiffany C.; Fox, Bernard A.; Mcdermott, Jason E., 0000-0003-2961-2572;
Chang, Shu-Ching; Grunkemeier, Gary; Leidner, Rom; Bell, Richard Bryan;
Weinberg, Andrew D. |
Nature Communications |
2018 |
| 25075 |
10.1038/s41577-019-0221-9 |
Defining ‘T Cell Exhaustion’ |
Blank, Christian U., 0000-0002-7945-5846; Haining, W.
Nicholas; Held, Werner, 0000-0003-3292-1536; Hogan, Patrick G.,
0000-0001-9869-0684; Kallies, Axel, 0000-0002-6312-6968; Lugli, Enrico,
0000-0002-1964-7678; Lynn, Rachel C., 0000-0002-0489-8634; Philip, Mary,
0000-0001-7496-2630; Rao, Anjana; Restifo, Nicholas P.; Schietinger,
Andrea, 0000-0003-3644-1687; Schumacher, Ton N., 0000-0003-0517-8804;
Schwartzberg, Pamela L., 0000-0001-6318-9187; Sharpe, Arlene H.,
0000-0002-9736-2109; Speiser, Daniel E., 0000-0003-2031-3250; Wherry, E.
John, 0000-0003-0477-1956; Youngblood, Benjamin A., 0000-0002-1261-9957;
Zehn, Dietmar, 0000-0003-1393-8527 |
Nature Reviews Immunology |
2019 |
| 25076 |
10.1038/s41577-019-0223-7 |
Precursor Exhausted T Cells: Key To Successful
Immunotherapy? |
Kallies, Axel, 0000-0002-6312-6968; Zehn, Dietmar,
0000-0003-1393-8527; Utzschneider, Daniel T. |
Nature Reviews Immunology |
2019 |
| 25499 |
10.1038/s41586-018-0130-2 |
Bystander Cd8+ T Cells Are Abundant And Phenotypically
Distinct In Human Tumour Infiltrates |
Simoni, Yannick; Becht, Etienne; Fehlings, Michael;
Loh, Chiew Yee; Koo, Si-Lin; Teng, Karen Wei Weng; Yeong, Joe Poh Sheng;
Nahar, Rahul; Zhang, Tong; Kared, Hassen; Duan, Kaibo; Ang, Nicholas;
Poidinger, Michael; Lee, Yin Yeng; Larbi, Anis; Khng, Alexis J.; Tan,
Emile; Fu, Cherylin; Mathew, Ronnie; Teo, Melissa; Lim, Wan Teck; Toh,
Chee Keong; Ong, Boon-Hean; Koh, Tina; Hillmer, Axel M.; Takano, Angela;
Lim, Tony Kiat Hon; Tan, Eng Huat; Zhai, Weiwei; Tan, Daniel S. W.; Tan,
Iain Beehuat; Newell, Evan W. |
Nature |
2018 |
| 25594 |
10.1038/s41586-018-0694-x |
Lineage Tracking Reveals Dynamic Relationships Of T
Cells In Colorectal Cancer |
Zhang, Lei; Yu, Xin; Zheng, Liangtao; Zhang, Yuanyuan;
Li, Yansen; Fang, Qiao; Gao, Ranran; Kang, Boxi; Zhang, Qiming; Huang,
Julie Y.; Konno, Hiroyasu; Guo, Xinyi; Ye, Yingjiang; Gao, Songyuan;
Wang, Shan; Hu, Xueda; Ren, Xianwen; Shen, Zhanlong; Ouyang, Wenjun;
Zhang, Zemin |
Nature |
2018 |
| 25685 |
10.1038/s41586-019-0979-8 |
Genome-Wide Analysis Identifies Nr4A1 As A Key Mediator
Of T Cell Dysfunction |
Liu, Xindong; Wang, Yun; Lu, Huiping; Li, Jing; Yan,
Xiaowei; Xiao, Minglu; Hao, Jing; Alekseev, Andrei; Khong, Hiep; Chen,
Tenghui; Huang, Rui; Wu, Jin; Zhao, Qiwen; Wu, Qi; Xu, Senlin; Wang,
Xiaohu; Jin, Wei; Yu, Shicang; Wang, Yan; Wei, Lai; Wang, Aibo; Zhong,
Bo; Ni, Ling; Liu, Xiaolong; Nurieva, Roza; Ye, Lilin; Tian, Qiang;
Bian, Xiu-Wu; Dong, Chen |
Nature |
2019 |
| 25688 |
10.1038/s41586-019-0985-x |
Nr4A Transcription Factors Limit Car T Cell Function In
Solid Tumours |
Chen, Joyce; Lopez-Moyado, Isaac F.; Seo, Hyungseok;
Lio, Chan-Wang J.; Hempleman, Laura J.; Sekiya, Takashi; Yoshimura,
Akihiko; Scott-Browne, James P.; Rao, Anjana |
Nature |
2019 |
| 25807 |
10.1038/s41586-019-1324-y |
Tox Is A Critical Regulator Of Tumour-Specific T Cell
Differentiation |
Scott, Andrew C.; Dundar, Friederike; Zumbo, Paul;
Chandran, Smita S.; Klebanoff, Christopher A.; Shakiba, Mojdeh; Trivedi,
Prerak; Menocal, Laura; Appleby, Heather; Camara, Steven; Zamarin,
Dmitriy; Walther, Tyler; Snyder, Alexandra; Femia, Matthew R.; Comen,
Elizabeth A.; Wen, Hannah Y.; Hellmann, Matthew D.; Anandasabapathy,
Niroshana; Liu, Yong; Altorki, Nasser K.; Lauer, Peter; Levy, Olivier;
Glickman, Michael S.; Kaye, Jonathan; Betel, Doron; Philip, Mary;
Schietinger, Andrea |
Nature |
2019 |
| 25808 |
10.1038/s41586-019-1325-x |
Tox Transcriptionally And Epigenetically Programs Cd8+
T Cell Exhaustion |
Khan, Omar; Giles, Josephine R.; Mcdonald, Sierra;
Manne, Sasikanth; Ngiow, Shin Foong; Patel, Kunal P.; Werner, Michael
T.; Huang, Alexander C.; Alexander, Katherine A.; Wu, Jennifer E.;
Attanasio, John; Yan, Patrick; George, Sangeeth M.; Bengsch, Bertram;
Staupe, Ryan P.; Donahue, Greg; Xu, Wei; Amaravadi, Ravi K.; Xu,
Xiaowei; Karakousis, Giorgos C.; Mitchell, Tara C.; Schuchter, Lynn M.;
Kaye, Jonathan; Berger, Shelley L.; Wherry, E. John |
Nature |
2019 |
| 25809 |
10.1038/s41586-019-1326-9 |
Tox Reinforces The Phenotype And Longevity Of Exhausted
T Cells In Chronic Viral Infection |
Alfei, Francesca; Kanev, Kristiyan; Hofmann, Maike; Wu,
Ming; Ghoneim, Hazem E.; Roelli, Patrick; Utzschneider, Daniel T.; Von
Hoesslin, Madlaina; Cullen, Jolie G.; Fan, Yiping; Eisenberg, Vasyl;
Wohlleber, Dirk; Steiger, Katja; Merkler, Doron; Delorenzi, Mauro;
Knolle, Percy A.; Cohen, Cyrille J.; Thimme, Robert; Youngblood,
Benjamin; Zehn, Dietmar |
Nature |
2019 |
| 25941 |
10.1038/s41586-019-1805-z |
C-Jun Overexpression In Car T Cells Induces Exhaustion
Resistance |
Lynn, Rachel C.; Weber, Evan W.; Sotillo, Elena;
Gennert, David; Xu, Peng; Good, Zinaida; Anbunathan, Hima; Lattin, John;
Jones, Robert; Tieu, Victor; Nagaraja, Surya; Granja, Jeffrey; De
Bourcy, Charles F. A.; Majzner, Robbie; Satpathy, Ansuman T.; Quake,
Stephen R.; Monje, Michelle; Chang, Howard Y.; Mackall, Crystal L. |
Nature |
2019 |
| 25948 |
10.1038/s41586-019-1836-5 |
An Intra-Tumoral Niche Maintains And Differentiates
Stem-Like Cd8 T Cells |
Jansen, Caroline S.; Prokhnevska, Nataliya; Master,
Viraj A.; Sanda, Martin G.; Carlisle, Jennifer W.; Bilen, Mehmet Asim;
Cardenas, Maria; Wilkinson, Scott; Lake, Ross; Sowalsky, Adam G.;
Valanparambil, Rajesh M.; Hudson, William H.; Mcguire, Donald; Melnick,
Kevin; Khan, Amir I.; Kim, Kyu; Chang, Yun Min; Kim, Alice; Filson,
Christopher P.; Alemozaffar, Mehrdad; Osunkoya, Adeboye O.; Mullane,
Patrick; Ellis, Carla; Akondy, Rama; Im, Se Jin; Kamphorst, Alice O.;
Reyes, Adriana; Liu, Yuan; Kissick, Haydn |
Nature |
2019 |
| 26008 |
10.1038/s41586-020-2056-8 |
Peripheral T Cell Expansion Predicts Tumour
Infiltration And Clinical Response |
Wu, Thomas D.; Madireddi, Shravan; De Almeida, Patricia
E.; Banchereau, Romain; Chen, Ying-Jiun J.; Chitre, Avantika S.; Chiang,
Eugene Y.; Iftikhar, Hina; O’Gorman, William E.; Au-Yeung, Amelia;
Takahashi, Chikara; Goldstein, Leonard D.; Poon, Chungkee; Keerthivasan,
Shilpa; De Almeida Nagata, Denise E.; Du, Xiangnan; Lee, Hyang-Mi;
Banta, Karl L.; Mariathasan, Sanjeev; Das Thakur, Meghna; Huseni,
Mahrukh A.; Ballinger, Marcus; Estay, Ivette; Caplazi, Patrick;
Modrusan, Zora; Delamarre, Lelia; Mellman, Ira; Bourgon, Richard;
Grogan, Jane L. |
Nature |
2020 |
| 26221 |
10.1038/s41587-019-0192-1 |
Car-T Cells Secreting Bites Circumvent Antigen Escape
Without Detectable Toxicity |
Choi, Bryan D.; Yu, Xiaoling; Castano, Ana P.;
Bouffard, Amanda A.; Schmidts, Andrea; Larson, Rebecca C.; Bailey,
Stefanie R., 0000-0002-1175-521X; Boroughs, Angela C.; Frigault, Matthew
J.; Leick, Mark B.; Scarfo, Irene, 0000-0002-5545-3248; Cetrulo, Curtis
L.; Demehri, Shadmehr; Nahed, Brian V.; Cahill, Daniel P.; Wakimoto,
Hiroaki, 0000-0001-8225-241X; Curry, William T.; Carter, Bob S.; Maus,
Marcela V., 0000-0002-7578-0393 |
Nature Biotechnology |
2019 |
| 26490 |
10.1038/s41590-019-0312-6 |
Subsets Of Exhausted Cd8+ T Cells Differentially
Mediate Tumor Control And Respond To Checkpoint Blockade |
Miller, Brian C., 0000-0001-5931-4184; Sen, Debattama
R., 0000-0002-0947-8284; Al Abosy, Rose, 0000-0001-5400-1306; Bi, Kevin;
Virkud, Yamini V.; Lafleur, Martin W., 0000-0002-5017-774X; Yates,
Kathleen B.; Lako, Ana; Felt, Kristen; Naik, Girish S.; Manos, Michael;
Gjini, Evisa; Kuchroo, Juhi R.; Ishizuka, Jeffrey J.; Collier, Jenna L.,
0000-0002-4071-4986; Griffin, Gabriel K.; Maleri, Seth; Comstock, Dawn
E.; Weiss, Sarah A.; Brown, Flavian D.; Panda, Arpit; Zimmer, Margaret
D.; Manguso, Robert T.; Hodi, F. Stephen; Rodig, Scott J.; Sharpe,
Arlene H.; Haining, W. Nicholas, 0000-0001-7871-3762 |
Nature Immunology |
2019 |
| 26501 |
10.1038/s41590-019-0403-4 |
Single-Cell Rna-Seq Reveals Tox As A Key Regulator Of
Cd8+ T Cell Persistence In Chronic Infection |
Yao, Chen; Sun, Hong-Wei; Lacey, Neal E.,
0000-0002-3633-5924; Ji, Yun; Moseman, E. Ashley; Shih, Han-Yu,
0000-0002-7525-5433; Heuston, Elisabeth F.; Kirby, Martha,
0000-0001-7157-7964; Anderson, Stacie; Cheng, Jun; Khan, Omar; Handon,
Robin; Reilley, Julie; Fioravanti, Jessica, 0000-0001-6263-4306; Hu,
Jinhui; Gossa, Selamawit; Wherry, E. John, 0000-0003-0477-1956;
Gattinoni, Luca, 0000-0003-2239-3282; Mcgavern, Dorian B.,
0000-0001-9568-545X; O’Shea, John J., 0000-0002-6456-9752; Schwartzberg,
Pamela L., 0000-0001-6318-9187; Wu, Tuoqi, 0000-0002-4003-1034 |
Nature Immunology |
2019 |
| 26533 |
10.1038/s41591-018-0036-4 |
Monocyte-Derived Il-1 And Il-6 Are Differentially
Required For Cytokine-Release Syndrome And Neurotoxicity Due To Car T
Cells |
Norelli, Margherita; Camisa, Barbara; Barbiera, Giulia;
Falcone, Laura; Purevdorj, Ayurzana; Genua, Marco; Sanvito, Francesca;
Ponzoni, Maurilio; Doglioni, Claudio, 0000-0002-4969-5216; Cristofori,
Patrizia; Traversari, Catia; Bordignon, Claudio; Ciceri, Fabio; Ostuni,
Renato; Bonini, Chiara; Casucci, Monica; Bondanza, Attilio |
Nature Medicine |
2018 |
| 26535 |
10.1038/s41591-018-0041-7 |
Car T Cell<U+2013>Induced Cytokine Release
Syndrome Is Mediated By Macrophages And Abated By Il-1 Blockade |
Giavridis, Theodoros, 0000-0002-8716-781X; Van Der
Stegen, Sjoukje J. C., 0000-0002-3839-3124; Eyquem, Justin; Hamieh,
Mohamad; Piersigilli, Alessandra; Sadelain, Michel |
Nature Medicine |
2018 |
| 26536 |
10.1038/s41591-018-0045-3 |
Global Characterization Of T Cells In Non-Small-Cell
Lung Cancer By Single-Cell Sequencing |
Guo, Xinyi; Zhang, Yuanyuan; Zheng, Liangtao; Zheng,
Chunhong; Song, Jintao; Zhang, Qiming; Kang, Boxi; Liu, Zhouzerui; Jin,
Liang; Xing, Rui; Gao, Ranran; Zhang, Lei; Dong, Minghui; Hu, Xueda;
Ren, Xianwen, 0000-0002-8558-5401; Kirchhoff, Dennis; Roider, Helge
Gottfried; Yan, Tiansheng; Zhang, Zemin, 0000-0003-3789-6536 |
Nature Medicine |
2018 |
| 26545 |
10.1038/s41591-018-0078-7 |
Single-Cell Profiling Of Breast Cancer T Cells Reveals
A Tissue-Resident Memory Subset Associated With Improved Prognosis |
Savas, Peter, 0000-0001-5999-428X; Virassamy, Balaji;
Ye, Chengzhong; Salim, Agus; Mintoff, Christopher P.; Caramia, Franco;
Salgado, Roberto; Byrne, David J.; Teo, Zhi L.; Dushyanthen, Sathana;
Byrne, Ann; Wein, Lironne; Luen, Stephen J.; Poliness, Catherine;
Nightingale, Sophie S.; Skandarajah, Anita S.; Gyorki, David E.;
Thornton, Chantel M.; Beavis, Paul A.; Fox, Stephen B.,
0000-0002-7648-8896; Darcy, Phillip K.; Speed, Terence P.; Mackay, Laura
K., 0000-0002-8496-6632; Neeson, Paul J.; Loi, Sherene,
0000-0001-6137-9171 |
Nature Medicine |
2018 |
| 26550 |
10.1038/s41591-018-0096-5 |
Phenotype Molding Of Stromal Cells In The Lung Tumor
Microenvironment |
Lambrechts, Diether, 0000-0002-3429-302X; Wauters, Els;
Boeckx, Bram; Aibar, Sara, 0000-0001-6104-7134; Nittner, David; Burton,
Oliver; Bassez, Ayse; Decaluwe, Herbert, 0000-0002-0877-7717; Pircher,
Andreas; Van Den Eynde, Kathleen; Weynand, Birgit, 0000-0003-4246-6303;
Verbeken, Erik; De Leyn, Paul; Liston, Adrian, 0000-0002-6272-4085;
Vansteenkiste, Johan, 0000-0002-6721-2775; Carmeliet, Peter; Aerts,
Stein; Thienpont, Bernard, 0000-0002-8772-6845 |
Nature Medicine |
2018 |
| 26598 |
10.1038/s41591-018-0290-5 |
Calibration Of Car Activation Potential Directs
Alternative T Cell Fates And Therapeutic Potency |
Feucht, Judith; Sun, Jie; Eyquem, Justin; Ho, Yu-Jui;
Zhao, Zeguo; Leibold, Josef; Dobrin, Anton; Cabriolu, Annalisa; Hamieh,
Mohamad; Sadelain, Michel, 0000-0002-9031-8025 |
Nature Medicine |
2018 |
| 26647 |
10.1038/s41591-019-0421-7 |
A Safe And Potent Anti-Cd19 Car T Cell Therapy |
Ying, Zhitao; Huang, Xue F.; Xiang, Xiaoyu; Liu,
Yanling; Kang, Xi; Song, Yuqin; Guo, Xiaokai; Liu, Hanzhi; Ding, Ning;
Zhang, Tingting; Duan, Panpan; Lin, Yufu; Zheng, Wen; Wang, Xiaopei;
Lin, Ningjing; Tu, Meifeng; Xie, Yan; Zhang, Chen; Liu, Weiping; Deng,
Lijuan; Gao, Shunyu; Ping, Lingyan; Wang, Xuejuan; Zhou, Nina; Zhang,
Junqing; Wang, Yulong; Lin, Songfeng; Mamuti, Mierzhati; Yu, Xueyun;
Fang, Lizhu; Wang, Shuai; Song, Haifeng; Wang, Guan; Jones, Lindsey;
Zhu, Jun, 0000-0003-3479-2547; Chen, Si-Yi, 0000-0003-2403-4988 |
Nature Medicine |
2019 |
| 26680 |
10.1038/s41591-019-0522-3 |
Clonal Replacement Of Tumor-Specific T Cells Following
Pd-1 Blockade |
Yost, Kathryn E.; Satpathy, Ansuman T.,
0000-0002-5167-537X; Wells, Daniel K.; Qi, Yanyan; Wang, Chunlin;
Kageyama, Robin; Mcnamara, Katherine L.; Granja, Jeffrey M.; Sarin,
Kavita Y., 0000-0001-5363-3053; Brown, Ryanne A.; Gupta, Rohit K.;
Curtis, Christina, 0000-0003-0166-3802; Bucktrout, Samantha L.; Davis,
Mark M., 0000-0001-6868-657X; Chang, Anne Lynn S., 0000-0002-2869-2147;
Chang, Howard Y., 0000-0002-9459-4393 |
Nature Medicine |
2019 |
| 26682 |
10.1038/s41591-019-0549-5 |
Enhanced Car T Cell Expansion And Prolonged Persistence
In Pediatric Patients With All Treated With A Low-Affinity Cd19 Car |
Ghorashian, Sara, 0000-0002-1555-2946; Kramer, Anne
Marijn; Onuoha, Shimobi; Wright, Gary; Bartram, Jack; Richardson,
Rachel; Albon, Sarah J.; Casanovas-Company, Joan; Castro, Fernanda;
Popova, Bilyana; Villanueva, Krystle; Yeung, Jenny; Vetharoy, Winston;
Guvenel, Aleks; Wawrzyniecka, Patrycja A., 0000-0002-4209-2834;
Mekkaoui, Leila, 0000-0001-8640-840X; Cheung, Gordon Weng-Kit; Pinner,
Danielle; Chu, Jan; Lucchini, Giovanna; Silva, Juliana; Ciocarlie, Oana;
Lazareva, Arina; Inglott, Sarah; Gilmour, Kimberly C.; Ahsan, Gulrukh;
Ferrari, Mathieu, 0000-0001-8535-7348; Manzoor, Somayya; Champion, Kim;
Brooks, Tony; Lopes, Andre; Hackshaw, Allan; Farzaneh, Farzin; Chiesa,
Robert; Rao, Kanchan; Bonney, Denise; Samarasinghe, Sujith; Goulden,
Nicholas; Vora, Ajay; Veys, Paul; Hough, Rachael; Wynn, Robert; Pule,
Martin A., 0000-0002-8347-9867; Amrolia, Persis J.,
0000-0003-0480-3911 |
Nature Medicine |
2019 |
| 26710 |
10.1038/s41591-019-0734-6 |
Peripheral Cd8+ T Cell Characteristics Associated With
Durable Responses To Immune Checkpoint Blockade In Patients With
Metastatic Melanoma |
Fairfax, Benjamin P., 0000-0001-7413-5002; Taylor,
Chelsea A.; Watson, Robert A.; Nassiri, Isar; Danielli, Sara; Fang, Hai,
0000-0003-3961-8572; Mahe, Elise A.; Cooper, Rosalin; Woodcock,
Victoria, 0000-0001-7656-728X; Traill, Zoe; Al-Mossawi, M. Hussein,
0000-0002-2312-3754; Knight, Julian C., 0000-0002-0377-5536; Klenerman,
Paul; Payne, Miranda; Middleton, Mark R., 0000-0003-0167-1685 |
Nature Medicine |
2020 |
| 26711 |
10.1038/s41591-019-0737-3 |
Safety And Feasibility Of Anti-Cd19 Car T Cells With
Fully Human Binding Domains In Patients With B-Cell Lymphoma |
Brudno, Jennifer N.; Lam, Norris; Vanasse, Danielle;
Shen, Yueh-Wei; Rose, Jeremy J.; Rossi, John; Xue, Allen; Bot, Adrian;
Scholler, Nathalie, 0000-0003-3743-7102; Mikkilineni, Lekha; Roschewski,
Mark; Dean, Robert; Cachau, Raul, 0000-0001-9260-2102; Youkharibache,
Philippe; Patel, Rashmika; Hansen, Brenna; Stroncek, David F.;
Rosenberg, Steven A.; Gress, Ronald E.; Kochenderfer, James N.,
0000-0002-4362-9875 |
Nature Medicine |
2020 |
| 26789 |
10.1038/s41591-020-1081-3 |
Bispecific Anti-Cd20, Anti-Cd19 Car T Cells For
Relapsed B Cell Malignancies: A Phase 1 Dose Escalation And Expansion
Trial |
Shah, Nirav N., 0000-0002-4336-1071; Johnson, Bryon D.;
Schneider, Dina; Zhu, Fenlu; Szabo, Aniko, 0000-0002-8129-0614;
Keever-Taylor, Carolyn A., 0000-0002-3085-6876; Krueger, Winfried;
Worden, Andrew A.; Kadan, Michael J.; Yim, Sharon, 0000-0001-6442-1320;
Cunningham, Ashley; Hamadani, Mehdi, 0000-0001-5372-510X; Fenske,
Timothy S.; Dropuli<U+0107>, Boro, 0000-0002-3861-7677; Orentas,
Rimas; Hari, Parameswaran |
Nature Medicine |
2020 |
| 29011 |
10.1056/nejmoa1804980 |
Tisagenlecleucel In Adult Relapsed Or Refractory
Diffuse Large B-Cell Lymphoma |
Schuster, Stephen J.; Bishop, Michael R.; Tam,
Constantine S.; Waller, Edmund K.; Borchmann, Peter; Mcguirk, Joseph P.;
Jager, Ulrich; Jaglowski, Samantha; Andreadis, Charalambos; Westin,
Jason R.; Fleury, Isabelle; Bachanova, Veronika; Foley, S. Ronan; Ho, P.
Joy; Mielke, Stephan; Magenau, John M.; Holte, Harald; Pantano,
Serafino; Pacaud, Lida B.; Awasthi, Rakesh; Chu, Jufen; Anak, Ozlem;
Salles, Gilles; Maziarz, Richard T. |
New England Journal Of Medicine |
2019 |
| 29017 |
10.1056/nejmoa1805104 |
Rituximab Plus Lenalidomide In Advanced Untreated
Follicular Lymphoma |
Morschhauser, Franck; Fowler, Nathan H.; Feugier,
Pierre; Bouabdallah, Reda; Tilly, Herve; Palomba, M. Lia; Fruchart,
Christophe; Libby, Edward N.; Casasnovas, Rene-Olivier; Flinn, Ian W.;
Haioun, Corinne; Maisonneuve, Herve; Ysebaert, Loic; Bartlett, Nancy L.;
Bouabdallah, Kamal; Brice, Pauline; Ribrag, Vincent; Daguindau, Nicolas;
Le Gouill, Steven; Pica, Gian M.; Martin Garcia-Sancho, Alejandro;
Lopez-Guillermo, Armando; Larouche, Jean-Francois; Ando, Kiyoshi; Gomes
Da Silva, Maria; Andre, Marc; Zachee, Pierre; Sehn, Laurie H.; Tobinai,
Kensei; Cartron, Guillaume; Liu, David; Wang, Jianming; Xerri, Luc;
Salles, Gilles A. |
New England Journal Of Medicine |
2018 |
| 29022 |
10.1056/nejmoa1805762 |
Elotuzumab Plus Pomalidomide And Dexamethasone For
Multiple Myeloma |
Dimopoulos, Meletios A.; Dytfeld, Dominik; Grosicki,
Sebastian; Moreau, Philippe; Takezako, Naoki; Hori, Mitsuo; Leleu,
Xavier; Leblanc, Richard; Suzuki, Kenshi; Raab, Marc S.; Richardson,
Paul G.; Popa Mckiver, Mihaela; Jou, Ying-Ming; Shelat, Suresh G.;
Robbins, Michael; Rafferty, Brian; San-Miguel, Jesus |
New England Journal Of Medicine |
2018 |
| 29117 |
10.1056/nejmoa1817226 |
Anti-Bcma Car T-Cell Therapy Bb2121 In Relapsed Or
Refractory Multiple Myeloma |
Raje, Noopur; Berdeja, Jesus; Lin, Yi; Siegel, David,
0000-0002-3604-2574; Jagannath, Sundar; Madduri, Deepu; Liedtke,
Michaela; Rosenblatt, Jacalyn; Maus, Marcela V.; Turka, Ashley; Lam,
Lyh-Ping; Morgan, Richard A.; Friedman, Kevin; Massaro, Monica; Wang,
Julie; Russotti, Greg; Yang, Zhihong; Campbell, Timothy; Hege, Kristen;
Petrocca, Fabio; Quigley, M. Travis; Munshi, Nikhil; Kochenderfer, James
N. |
New England Journal Of Medicine |
2019 |
| 29118 |
10.1056/nejmoa1817249 |
Daratumumab Plus Lenalidomide And Dexamethasone For
Untreated Myeloma |
Facon, Thierry; Kumar, Shaji; Plesner, Torben;
Orlowski, Robert Z.; Moreau, Philippe; Bahlis, Nizar; Basu, Supratik;
Nahi, Hareth; Hulin, Cyrille; Quach, Hang; Goldschmidt, Hartmut;
O’Dwyer, Michael; Perrot, Aurore; Venner, Christopher P.; Weisel, Katja;
Mace, Joseph R.; Raje, Noopur; Attal, Michel; Tiab, Mourad; Macro,
Margaret; Frenzel, Laurent; Leleu, Xavier; Ahmadi, Tahamtan; Chiu,
Christopher; Wang, Jianping; Van Rampelbergh, Rian; Uhlar, Clarissa M.;
Kobos, Rachel; Qi, Ming; Usmani, Saad Z. |
New England Journal Of Medicine |
2019 |
| 29151 |
10.1056/nejmoa1903455 |
Oral Selinexor<U+2013>Dexamethasone For
Triple-Class Refractory Multiple Myeloma |
Chari, Ajai; Vogl, Dan T.; Gavriatopoulou, Maria;
Nooka, Ajay K.; Yee, Andrew J.; Huff, Carol A.; Moreau, Philippe;
Dingli, David; Cole, Craig; Lonial, Sagar; Dimopoulos, Meletios;
Stewart, A. Keith; Richter, Joshua; Vij, Ravi; Tuchman, Sascha; Raab,
Marc S.; Weisel, Katja C.; Delforge, Michel; Cornell, Robert F.;
Kaminetzky, David; Hoffman, James E.; Costa, Luciano J.,
0000-0001-5362-2469; Parker, Terri L.; Levy, Moshe; Schreder, Martin;
Meuleman, Nathalie; Frenzel, Laurent; Mohty, Mohamad; Choquet, Sylvain;
Schiller, Gary; Comenzo, Raymond L.; Engelhardt, Monika; Illmer, Thomas;
Vlummens, Philip; Doyen, Chantal; Facon, Thierry; Karlin, Lionel;
Perrot, Aurore; Podar, Klaus; Kauffman, Michael G.; Shacham, Sharon; Li,
Lingling; Tang, Shijie; Picklesimer, Carla; Saint-Martin, Jean-Richard;
Crochiere, Marsha; Chang, Hua; Parekh, Samir; Landesman, Yosef; Shah,
Jatin; Richardson, Paul G.; Jagannath, Sundar |
New England Journal Of Medicine |
2019 |
| 29228 |
10.1056/nejmoa1914347 |
Kte-X19 Car T-Cell Therapy In Relapsed Or Refractory
Mantle-Cell Lymphoma |
Wang, Michael, 0000-0001-9748-5486; Munoz, Javier; Goy,
Andre; Locke, Frederick L.; Jacobson, Caron A.; Hill, Brian T.;
Timmerman, John M.; Holmes, Houston; Jaglowski, Samantha; Flinn, Ian W.;
Mcsweeney, Peter A.; Miklos, David B.; Pagel, John M.; Kersten,
Marie-Jose; Milpied, Noel; Fung, Henry; Topp, Max S.,
0000-0002-1267-5289; Houot, Roch; Beitinjaneh, Amer; Peng, Weimin;
Zheng, Lianqing; Rossi, John M.; Jain, Rajul K.; Rao, Arati V.; Reagan,
Patrick M. |
New England Journal Of Medicine |
2020 |
| 29308 |
10.1056/nejmoa2024850 |
Idecabtagene Vicleucel In Relapsed And Refractory
Multiple Myeloma |
Munshi, Nikhil C.; Anderson, Larry D.; Shah, Nina;
Madduri, Deepu; Berdeja, Jesus; Lonial, Sagar; Raje, Noopur; Lin, Yi;
Siegel, David, 0000-0002-3604-2574; Oriol, Albert; Moreau, Philippe;
Yakoub-Agha, Ibrahim, 0000-0003-4524-8782; Delforge, Michel; Cavo,
Michele; Einsele, Hermann; Goldschmidt, Hartmut; Weisel, Katja;
Rambaldi, Alessandro; Reece, Donna; Petrocca, Fabio; Massaro, Monica;
Connarn, Jamie N.; Kaiser, Shari; Patel, Payal; Huang, Liping; Campbell,
Timothy B.; Hege, Kristen; San-Miguel, Jesus |
New England Journal Of Medicine |
2021 |
| 29654 |
10.1073/pnas.1819745116 |
Exploratory Trial Of A Biepitopic Car T-Targeting B
Cell Maturation Antigen In Relapsed/Refractory Multiple Myeloma |
Xu, Jie; Chen, Li-Juan; Yang, Shuang-Shuang; Sun, Yan;
Wu, Wen; Liu, Yuan-Fang; Xu, Ji; Zhuang, Yan; Zhang, Wu; Weng,
Xiang-Qin; Wu, Jing; Wang, Yan; Wang, Jin; Yan, Hua; Xu, Wen-Bin; Jiang,
Hua; Du, Juan; Ding, Xiao-Yi; Li, Biao; Li, Jun-Min; Fu, Wei-Jun; Zhu,
Jiang; Zhu, Li; Chen, Zhu; Fan, Xiao-Hu (Frank); Hou, Jian; Li,
Jian-Yong; Mi, Jian-Qing; Chen, Sai-Juan |
Proceedings Of The National Academy Of Sciences |
2019 |
| 29690 |
10.1073/pnas.1905675116 |
Tox And Tox2 Transcription Factors Cooperate With Nr4A
Transcription Factors To Impose Cd8+ T Cell Exhaustion |
Seo, Hyungseok, 0000-0002-6632-1208; Chen, Joyce;
Gonzalez-Avalos, Edahi; Samaniego-Castruita, Daniela; Das, Arundhoti;
Wang, Yueqiang H.; Lopez-Moyado, Isaac F.; Georges, Romain O.; Zhang,
Wade; Onodera, Atsushi; Wu, Cheng-Jang, 0000-0002-7640-5915; Lu, Li-Fan;
Hogan, Patrick G.; Bhandoola, Avinash, 0000-0002-4657-8372; Rao, Anjana,
0000-0002-1870-1775 |
Proceedings Of The National Academy Of Sciences |
2019 |
| 30252 |
10.1084/jem.20180684 |
High-Dimensional Single Cell Analysis Identifies
Stem-Like Cytotoxic Cd8+ T Cells Infiltrating Human Tumors |
Brummelman, Jolanda, 0000-0003-3581-4816; Mazza, Emilia
M.C.; Alvisi, Giorgia; Colombo, Federico S., 0000-0003-4480-3481;
Grilli, Andrea, 0000-0002-6219-0714; Mikulak, Joanna; Mavilio, Domenico,
0000-0001-6147-0952; Alloisio, Marco; Ferrari, Francesco; Lopci, Egesta;
Novellis, Pierluigi; Veronesi, Giulia; Lugli, Enrico,
0000-0002-1964-7678 |
Journal Of Experimental Medicine |
2018 |
| 31442 |
10.1097/cji.0000000000000260 |
Pilot Trial Of Adoptive Transfer Of Chimeric Antigen
Receptor<U+2013>Transduced T Cells Targeting Egfrviii In Patients
With Glioblastoma |
Goff, Stephanie L.; Morgan, Richard A.; Yang, James C.;
Sherry, Richard M.; Robbins, Paul F.; Restifo, Nicholas P.; Feldman,
Steven A.; Lu, Yong-Chen; Lu, Lily; Zheng, Zhili; Xi, Liqiang; Epstein,
Monica; Mcintyre, Lori S.; Malekzadeh, Parisa; Raffeld, Mark; Fine,
Howard A.; Rosenberg, Steven A. |
Journal Of Immunotherapy |
2019 |
| 34067 |
10.1126/scisignal.aat6753 |
Phosphoproteomic Analysis Of Chimeric Antigen Receptor
Signaling Reveals Kinetic And Quantitative Differences That Affect Cell
Function |
Salter, Alexander I., 0000-0003-3820-0895; Ivey,
Richard G.; Kennedy, Jacob J.; Voillet, Valentin; Rajan, Anusha,
0000-0002-0036-4301; Alderman, Eva J.; Voytovich, Uliana J.,
0000-0002-7235-1577; Lin, Chenwei; Sommermeyer, Daniel; Liu, Lingfeng;
Whiteaker, Jeffrey R., 0000-0001-5042-8580; Gottardo, Raphael,
0000-0002-3867-0232; Paulovich, Amanda G.; Riddell, Stanley R.,
0000-0002-4688-9920 |
Science Signaling |
2018 |
| 34099 |
10.1126/scitranslmed.aau5907 |
The Tyrosine Kinase Inhibitor Dasatinib Acts As A
Pharmacologic On/Off Switch For Car T Cells |
Mestermann, Katrin, 0000-0002-3585-5055; Giavridis,
Theodoros; Weber, Justus; Rydzek, Julian; Frenz, Silke,
0000-0002-2026-2177; Nerreter, Thomas, 0000-0002-0493-1369; Mades,
Andreas, 0000-0001-7322-2817; Sadelain, Michel, 0000-0002-9031-8025;
Einsele, Hermann; Hudecek, Michael, 0000-0002-2280-2202 |
Science Translational Medicine |
2019 |
| 34102 |
10.1126/scitranslmed.aau7746 |
Gprc5D Is A Target For The Immunotherapy Of Multiple
Myeloma With Rationally Designed Car T Cells |
Smith, Eric L., 0000-0002-0296-7587; Harrington, Kim;
Staehr, Mette, 0000-0001-8680-4373; Masakayan, Reed,
0000-0003-3591-8869; Jones, Jon, 0000-0003-3870-3337; Long, Thomas J.;
Ng, Khong Y., 0000-0003-4373-850X; Ghoddusi, Majid, 0000-0001-7552-2418;
Purdon, Terence J.; Wang, Xiuyan; Do, Trevor; Pham, Minh Thu; Brown,
Jessica M., 0000-0001-9031-9987; De Larrea, Carlos Fernandez; Olson,
Eric; Peguero, Elizabeth, 0000-0003-2387-3595; Wang, Pei; Liu, Hong; Xu,
Yiyang; Garrett-Thomson, Sarah C., 0000-0002-3073-1571; Almo, Steven C.;
Wendel, Hans-Guido, 0000-0001-7166-4670; Riviere, Isabelle; Liu, Cheng;
Sather, Blythe, 0000-0001-6582-0243; Brentjens, Renier J.,
0000-0002-3364-5388 |
Science Translational Medicine |
2019 |
| 34772 |
10.1146/annurev-immunol-041015-055318 |
Cd8 T Cell Exhaustion During Chronic Viral Infection
And Cancer |
Mclane, Laura M.; Abdel-Hakeem, Mohamed S.; Wherry, E.
John |
Annual Review Of Immunology |
2019 |
| 35104 |
10.1158/1078-0432.ccr-18-1597 |
The Mechanism Of Action Of The Anti-Cd38 Monoclonal
Antibody Isatuximab In Multiple Myeloma |
Moreno, Laura; Perez, Cristina; Zabaleta, Aintzane;
Manrique, Irene; Alignani, Diego; Ajona, Daniel; Blanco, Laura; Lasa,
Marta; Maiso, Patricia; Rodriguez, Idoia; Garate, Sonia; Jelinek, Tomas;
Segura, Victor; Moreno, Cristina; Merino, Juana; Rodriguez-Otero, Paula;
Panizo, Carlos; Prosper, Felipe; San-Miguel, Jesus F.; Paiva, Bruno |
Clinical Cancer Research |
2019 |
| 35141 |
10.1158/2159-8290.cd-17-1319 |
Clinical And Biological Correlates Of Neurotoxicity
Associated With Car T-Cell Therapy In Patients With B-Cell Acute
Lymphoblastic Leukemia |
Santomasso, Bianca D., 0000-0001-9423-4059; Park, Jae
H.; Salloum, Darin; Riviere, Isabelle; Flynn, Jessica; Mead, Elena;
Halton, Elizabeth; Wang, Xiuyan; Senechal, Brigitte; Purdon, Terence;
Cross, Justin R.; Liu, Hui; Vachha, Behroze; Chen, Xi; Deangelis, Lisa
M.; Li, Daniel; Bernal, Yvette; Gonen, Mithat; Wendel, Hans-Guido;
Sadelain, Michel; Brentjens, Renier J. |
Cancer Discovery |
2018 |
| 35560 |
10.1172/jci126397 |
B Cell Maturation Antigen<U+2013>Specific Car T
Cells Are Clinically Active In Multiple Myeloma |
Cohen, Adam D.; Garfall, Alfred L.,
0000-0003-2791-5748; Stadtmauer, Edward A.; Melenhorst, J. Joseph;
Lacey, Simon F., 0000-0003-2882-1962; Lancaster, Eric; Vogl, Dan T.,
0000-0002-2935-2566; Weiss, Brendan M.; Dengel, Karen; Nelson,
Annemarie; Plesa, Gabriela; Chen, Fang; Davis, Megan M.,
0000-0003-4221-7876; Hwang, Wei-Ting; Young, Regina M.; Brogdon,
Jennifer L.; Isaacs, Randi, 0000-0003-0433-8976; Pruteanu-Malinici,
Iulian; Siegel, Don L., 0000-0003-2098-2251; Levine, Bruce L.,
0000-0001-6971-8465; June, Carl H., 0000-0003-0241-3557; Milone, Michael
C. |
Journal Of Clinical Investigation |
2019 |
| 35848 |
10.1182/blood-2018-06-858613 |
Minimal Residual Disease Negativity Using Deep
Sequencing Is A Major Prognostic Factor In Multiple Myeloma |
Perrot, Aurore, 0000-0003-0131-8689; Lauwers-Cances,
Valerie; Corre, Jill; Robillard, Nelly; Hulin, Cyrille; Chretien,
Marie-Lorraine; Dejoie, Thomas; Maheo, Sabrina; Stoppa, Anne-Marie;
Pegourie, Brigitte; Karlin, Lionel; Garderet, Laurent; Arnulf, Bertrand;
Doyen, Chantal; Meuleman, Nathalie; Royer, Bruno; Eveillard,
Jean-Richard; Benboubker, Lotfi; Dib, Mamoun; Decaux, Olivier; Jaccard,
Arnaud; Belhadj, Karim; Brechignac, Sabine; Kolb, Brigitte; Fohrer,
Cecile; Mohty, Mohamad; Macro, Margaret; Richardson, Paul G.; Carlton,
Victoria; Moorhead, Martin; Willis, Tom; Faham, Malek; Anderson, Kenneth
C.; Harousseau, Jean-Luc; Leleu, Xavier; Facon, Thierry; Moreau,
Philippe; Attal, Michel; Avet-Loiseau, Herve; Munshi, Nikhil |
Blood |
2018 |
| 35862 |
10.1182/blood-2018-10-881722 |
Gm-Csf Inhibition Reduces Cytokine Release Syndrome And
Neuroinflammation But Enhances Car-T Cell Function In Xenografts |
Sterner, Rosalie M.; Sakemura, Reona; Cox, Michelle J.;
Yang, Nan; Khadka, Roman H.; Forsman, Cynthia L.; Hansen, Michael J.;
Jin, Fang; Ayasoufi, Katayoun; Hefazi, Mehrdad; Schick, Kendall J.;
Walters, Denise K.; Ahmed, Omar; Chappell, Dale; Sahmoud, Tarek;
Durrant, Cameron; Nevala, Wendy K.; Patnaik, Mrinal M.; Pease, Larry R.;
Hedin, Karen E.; Kay, Neil E.; Johnson, Aaron J.; Kenderian, Saad
S. |
Blood |
2019 |
| 35868 |
10.1182/blood-2018-11-883710 |
Factors Associated With Durable Efs In Adult B-Cell All
Patients Achieving Mrd-Negative Cr After Cd19 Car T-Cell Therapy |
Hay, Kevin A., 0000-0002-9398-2677; Gauthier, Jordan,
0000-0002-5769-8409; Hirayama, Alexandre V., 0000-0001-7980-3882;
Voutsinas, Jenna M.; Wu, Qian, 0000-0002-2292-4816; Li, Daniel; Gooley,
Ted A., 0000-0002-8182-3652; Cherian, Sindhu; Chen, Xueyan; Pender,
Barbara S.; Hawkins, Reed M., 0000-0001-8611-2588; Vakil, Aesha;
Steinmetz, Rachel N.; Schoch, Gary; Chapuis, Aude G.,
0000-0002-9574-5448; Till, Brian G., 0000-0002-4718-8288; Kiem,
Hans-Peter, 0000-0001-5949-4947; Ramos, Jorge D.; Shadman, Mazyar;
Cassaday, Ryan D., 0000-0002-3424-2425; Acharya, Utkarsh H.,
0000-0002-5920-2796; Riddell, Stanley R., 0000-0002-4688-9920; Maloney,
David G., 0000-0002-8477-6919; Turtle, Cameron J.,
0000-0002-4722-4461 |
Blood |
2019 |
| 35869 |
10.1182/blood-2018-11-887067 |
The Response To Lymphodepletion Impacts Pfs In Patients
With Aggressive Non-Hodgkin Lymphoma Treated With Cd19 Car T Cells |
Hirayama, Alexandre V., 0000-0001-7980-3882; Gauthier,
Jordan, 0000-0002-5769-8409; Hay, Kevin A., 0000-0002-9398-2677;
Voutsinas, Jenna M.; Wu, Qian; Gooley, Ted; Li, Daniel; Cherian, Sindhu;
Chen, Xueyan; Pender, Barbara S.; Hawkins, Reed M., 0000-0001-8611-2588;
Vakil, Aesha; Steinmetz, Rachel N., 0000-0001-8847-112X; Acharya,
Utkarsh H., 0000-0002-5920-2796; Cassaday, Ryan D., 0000-0002-3424-2425;
Chapuis, Aude G., 0000-0002-9574-5448; Dhawale, Tejaswini M.,
0000-0003-0163-2061; Hendrie, Paul C., 0000-0003-1902-5972; Kiem,
Hans-Peter, 0000-0001-5949-4947; Lynch, Ryan C., 0000-0001-6703-0894;
Ramos, Jorge; Shadman, Mazyar; Till, Brian G., 0000-0002-4718-8288;
Riddell, Stanley R., 0000-0002-4688-9920; Maloney, David G.,
0000-0002-8477-6919; Turtle, Cameron J., 0000-0002-4722-4461 |
Blood |
2019 |
| 35870 |
10.1182/blood-2018-12-893396 |
Clinical Presentation, Management, And Biomarkers Of
Neurotoxicity After Adoptive Immunotherapy With Car T Cells |
Karschnia, Philipp, 0000-0002-1254-5310; Jordan, Justin
T.; Forst, Deborah A.; Arrillaga-Romany, Isabel C.; Batchelor, Tracy T.;
Baehring, Joachim M.; Clement, Nathan F.; Gonzalez Castro, L. Nicolas;
Herlopian, Aline, 0000-0002-0189-7011; Maus, Marcela V.; Schwaiblmair,
Michaela H.; Soumerai, Jacob D.; Takvorian, Ronald W.; Hochberg, Ephraim
P., 0000-0001-9050-7208; Barnes, Jeffrey A.; Abramson, Jeremy S.;
Frigault, Matthew J.; Dietrich, Jorg |
Blood |
2019 |
| 35872 |
10.1182/blood-2019-123742 |
Mosunetuzumab Induces Complete Remissions In Poor
Prognosis Non-Hodgkin Lymphoma Patients, Including Those Who Are
Resistant To Or Relapsing After Chimeric Antigen Receptor T-Cell (Car-T)
Therapies, And Is Active In Treatment Through Multiple Lines |
Schuster, Stephen J; Bartlett, Nancy L; Assouline,
Sarit; Yoon, Sung-Soo; Bosch, Francesc; Sehn, Laurie H; Cheah, Chan Y.;
Shadman, Mazyar; Gregory, Gareth P; Ku, Matthew; Wei, Michael C; Yin,
Shen; Kwan, Antonia; Yousefi, Kasra; Hernandez, Genevive; Li, Chi-Chung;
O’Hear, Carol; Budde, Lihua E |
Blood |
2019 |
| 35876 |
10.1182/blood.2019000050 |
Γ-Secretase Inhibition Increases Efficacy Of
Bcma-Specific Chimeric Antigen Receptor T Cells In Multiple Myeloma |
Pont, Margot J., 0000-0002-5934-9990; Hill, Tyler,
0000-0002-9192-8327; Cole, Gabriel O., 0000-0003-0135-2406; Abbott, Joe
J.; Kelliher, Jessica; Salter, Alexander I., 0000-0003-3820-0895;
Hudecek, Michael; Comstock, Melissa L.; Rajan, Anusha,
0000-0002-0036-4301; Patel, Bharvin K. R.; Voutsinas, Jenna M.; Wu,
Qian; Liu, Lingfeng, 0000-0001-6182-9822; Cowan, Andrew J.; Wood, Brent
L.; Green, Damian J., 0000-0003-0477-1446; Riddell, Stanley R. |
Blood |
2019 |
| 35879 |
10.1182/blood.2019000722 |
Daratumumab Plus Carfilzomib And Dexamethasone In
Patients With Relapsed Or Refractory Multiple Myeloma |
Chari, Ajai; Martinez-Lopez, Joaquin,
0000-0001-7908-0063; Mateos, Maria-Victoria; Blade, Joan; Benboubker,
Lotfi, 0000-0003-0167-8836; Oriol, Albert, 0000-0001-6804-2221; Arnulf,
Bertrand; Rodriguez-Otero, Paula; Pineiro, Luis; Jakubowiak, Andrzej; De
Boer, Carla; Wang, Jianping; Clemens, Pamela L.; Ukropec, Jon; Schecter,
Jordan; Lonial, Sagar; Moreau, Philippe |
Blood |
2019 |
| 35880 |
10.1182/blood.2019000905 |
High Rate Of Durable Complete Remission In Follicular
Lymphoma After Cd19 Car-T Cell Immunotherapy |
Hirayama, Alexandre V., 0000-0001-7980-3882; Gauthier,
Jordan, 0000-0002-5769-8409; Hay, Kevin A., 0000-0002-9398-2677;
Voutsinas, Jenna M.; Wu, Qian; Pender, Barbara S.; Hawkins, Reed M.,
0000-0001-8611-2588; Vakil, Aesha; Steinmetz, Rachel N.,
0000-0001-8847-112X; Riddell, Stanley R., 0000-0002-4688-9920; Maloney,
David G., 0000-0002-8477-6919; Turtle, Cameron J.,
0000-0002-4722-4461 |
Blood |
2019 |
| 35884 |
10.1182/blood.2019001463 |
Preemptive Mitigation Of Cd19 Car T-Cell Cytokine
Release Syndrome Without Attenuation Of Antileukemic Efficacy |
Gardner, Rebecca A.; Ceppi, Francesco; Rivers, Julie;
Annesley, Colleen; Summers, Corinne, 0000-0003-1769-7388; Taraseviciute,
Agne; Gust, Juliane; Leger, Kasey J., 0000-0002-7905-6714; Tarlock,
Katherine; Cooper, Todd M.; Finney, Olivia C.; Brakke, Hannah; Li,
Daniel H.; Park, Julie R.; Jensen, Michael C. |
Blood |
2019 |
| 35885 |
10.1182/blood.2019001641 |
Toxicity And Response After Cd19-Specific Car T-Cell
Therapy In Pediatric/Young Adult Relapsed/Refractory B-All |
Curran, Kevin J., 0000-0002-3337-9956; Margossian,
Steven P.; Kernan, Nancy A.; Silverman, Lewis B.; Williams, David A.;
Shukla, Neerav; Kobos, Rachel; Forlenza, Christopher J.; Steinherz,
Peter; Prockop, Susan; Boulad, Farid; Spitzer, Barbara; Cancio, Maria
I.; Boelens, Jaap Jan, 0000-0003-2232-6952; Kung, Andrew L.; Khakoo,
Yasmin; Szenes, Victoria; Park, Jae H.; Sauter, Craig S.; Heller, Glenn;
Wang, Xiuyan; Senechal, Brigitte; O’Reilly, Richard J.; Riviere,
Isabelle; Sadelain, Michel, 0000-0002-9031-8025; Brentjens, Renier
J. |
Blood |
2019 |
| 35893 |
10.1182/blood.2020005288 |
Daratumumab, Lenalidomide, Bortezomib, And
Dexamethasone For Transplant-Eligible Newly Diagnosed Multiple Myeloma:
The Griffin Trial |
Voorhees, Peter M.; Kaufman, Jonathan L.; Laubach,
Jacob; Sborov, Douglas W.; Reeves, Brandi; Rodriguez, Cesar; Chari,
Ajai; Silbermann, Rebecca; Costa, Luciano J., 0000-0001-5362-2469;
Anderson, Larry D., 0000-0002-6531-9595; Nathwani, Nitya; Shah, Nina;
Efebera, Yvonne A.; Holstein, Sarah A., 0000-0002-9342-5635; Costello,
Caitlin; Jakubowiak, Andrzej; Wildes, Tanya M.; Orlowski, Robert Z.,
0000-0002-5723-4129; Shain, Kenneth H.; Cowan, Andrew J.; Murphy, Sean;
Lutska, Yana; Pei, Huiling; Ukropec, Jon; Vermeulen, Jessica; De Boer,
Carla; Hoehn, Daniela; Lin, Thomas S.; Richardson, Paul G. |
Blood |
2020 |
| 36320 |
10.1186/s13045-018-0681-6 |
A Phase 1, Open-Label Study Of Lcar-B38M, A Chimeric
Antigen Receptor T Cell Therapy Directed Against B Cell Maturation
Antigen, In Patients With Relapsed Or Refractory Multiple Myeloma |
Zhao, Wan-Hong; Liu, Jie; Wang, Bai-Yan; Chen, Yin-Xia;
Cao, Xing-Mei; Yang, Yun; Zhang, Yi-Lin; Wang, Fang-Xia; Zhang, Peng-Yu;
Lei, Bo; Gu, Liu-Fang; Wang, Jian-Li; Yang, Nan; Zhang, Ru; Zhang, Hui;
Shen, Ying; Bai, Ju; Xu, Yan; Wang, Xu-Geng; Zhang, Rui-Li; Wei, Li-Li;
Li, Zong-Fang; Li, Zhen-Zhen; Geng, Yan; He, Qian; Zhuang, Qiu-Chuan;
Fan, Xiao-Hu; He, Ai-Li; Zhang, Wang-Gang |
Journal Of Hematology & Oncology |
2018 |
| 36654 |
10.1200/jco.18.00685 |
Autologous Transplantation, Consolidation, And
Maintenance Therapy In Multiple Myeloma: Results Of The Bmt Ctn 0702
Trial |
Stadtmauer, Edward A.; Pasquini, Marcelo C.; Blackwell,
Beth; Hari, Parameswaran; Bashey, Asad; Devine, Steven; Efebera, Yvonne;
Ganguly, Siddharta; Gasparetto, Cristina; Geller, Nancy; Horowitz, Mary
M.; Koreth, John; Knust, Kristin; Landau, Heather; Brunstein, Claudio;
Mccarthy, Philip; Nelson, Courtney; Qazilbash, Muzaffar H.; Shah, Nina;
Vesole, David H.; Vij, Ravi; Vogl, Dan T.; Giralt, Sergio; Somlo,
George; Krishnan, Amrita |
Journal Of Clinical Oncology |
2019 |
| 36656 |
10.1200/jco.18.00915 |
Dynamo: A Phase Ii Study Of Duvelisib (Ipi-145) In
Patients With Refractory Indolent Non-Hodgkin Lymphoma |
Flinn, Ian W.; Miller, Carole B.; Ardeshna, Kirit M.;
Tetreault, Scott; Assouline, Sarit E.; Mayer, Jiri; Merli, Michele;
Lunin, Scott D.; Pettitt, Andrew R.; Nagy, Zoltan; Tournilhac, Olivier;
Abou-Nassar, Karem-Etienne; Crump, Michael; Jacobsen, Eric D.; De Vos,
Sven; Kelly, Virginia M.; Shi, Weiliang; Steelman, Lori; Le, Ngocdiep;
Weaver, David T.; Lustgarten, Stephanie; Wagner-Johnston, Nina D.;
Zinzani, Pier Luigi |
Journal Of Clinical Oncology |
2019 |
| 36697 |
10.1200/jco.19.00010 |
Augment: A Phase Iii Study Of Lenalidomide Plus
Rituximab Versus Placebo Plus Rituximab In Relapsed Or Refractory
Indolent Lymphoma |
Leonard, John P.; Trneny, Marek; Izutsu, Koji; Fowler,
Nathan H.; Hong, Xiaonan; Zhu, Jun; Zhang, Huilai; Offner, Fritz;
Scheliga, Adriana; Nowakowski, Grzegorz S.; Pinto, Antonio; Re,
Francesca; Fogliatto, Laura Maria; Scheinberg, Phillip; Flinn, Ian W.;
Moreira, Claudia; Cabecadas, Jose; Liu, David; Kalambakas, Stacey;
Fustier, Pierre; Wu, Chengqing; Gribben, John G. |
Journal Of Clinical Oncology |
2019 |
| 36700 |
10.1200/jco.19.00172 |
Polatuzumab Vedotin In Relapsed Or Refractory Diffuse
Large B-Cell Lymphoma |
Sehn, Laurie H.; Herrera, Alex F.; Flowers, Christopher
R.; Kamdar, Manali K.; Mcmillan, Andrew; Hertzberg, Mark; Assouline,
Sarit; Kim, Tae Min; Kim, Won Seog; Ozcan, Muhit; Hirata, Jamie; Penuel,
Elicia; Paulson, Joseph N.; Cheng, Ji; Ku, Grace; Matasar, Matthew
J. |
Journal Of Clinical Oncology |
2020 |
| 36731 |
10.1200/jco.19.02104 |
Standard-Of-Care Axicabtagene Ciloleucel For Relapsed
Or Refractory Large B-Cell Lymphoma: Results From The Us Lymphoma Car T
Consortium |
Nastoupil, Loretta J.; Jain, Michael D.; Feng, Lei;
Spiegel, Jay Y.; Ghobadi, Armin; Lin, Yi; Dahiya, Saurabh; Lunning,
Matthew; Lekakis, Lazaros; Reagan, Patrick; Oluwole, Olalekan; Mcguirk,
Joseph; Deol, Abhinav; Sehgal, Alison R.; Goy, Andre; Hill, Brian T.;
Vu, Khoan; Andreadis, Charalambos; Munoz, Javier; Westin, Jason; Chavez,
Julio C.; Cashen, Amanda; Bennani, N. Nora; Rapoport, Aaron P.; Vose,
Julie M.; Miklos, David B.; Neelapu, Sattva S.; Locke, Frederick L. |
Journal Of Clinical Oncology |
2020 |
| 36739 |
10.1200/jco.19.02657 |
Anti<U+2013>B-Cell Maturation Antigen Bite
Molecule Amg 420 Induces Responses In Multiple Myeloma |
Topp, Max S.; Duell, Johannes; Zugmaier, Gerhard;
Attal, Michel; Moreau, Philippe; Langer, Christian; Kronke, Jan; Facon,
Thierry; Salnikov, Alexey V.; Lesley, Robin; Beutner, Karl; Kalabus,
James; Rasmussen, Erik; Riemann, Kathrin; Minella, Alex C.; Munzert,
Gerd; Einsele, Hermann |
Journal Of Clinical Oncology |
2020 |
| 36745 |
10.1200/jco.19.03279 |
Cd4/Cd8 T-Cell Selection Affects Chimeric Antigen
Receptor (Car) T-Cell Potency And Toxicity: Updated Results From A Phase
I Anti-Cd22 Car T-Cell Trial |
Shah, Nirali N.; Highfill, Steven L.; Shalabi, Haneen;
Yates, Bonnie; Jin, Jianjian; Wolters, Pamela L.; Ombrello, Amanda;
Steinberg, Seth M.; Martin, Staci; Delbrook, Cindy; Hoffman, Leah;
Little, Lauren; Ponduri, Anusha; Qin, Haiying; Qureshi, Haris;
Dulau-Florea, Alina; Salem, Dalia; Wang, Hao-Wei; Yuan, Constance;
Stetler-Stevenson, Maryalice; Panch, Sandhya; Tran, Minh; Mackall,
Crystal L.; Stroncek, David F.; Fry, Terry J. |
Journal Of Clinical Oncology |
2020 |
| 36779 |
10.1200/jco.2018.77.8084 |
T Cells Genetically Modified To Express An
Anti<U+2013>B-Cell Maturation Antigen Chimeric Antigen Receptor
Cause Remissions Of Poor-Prognosis Relapsed Multiple Myeloma |
Brudno, Jennifer N.; Maric, Irina; Hartman, Steven D.;
Rose, Jeremy J.; Wang, Michael; Lam, Norris; Stetler-Stevenson,
Maryalice; Salem, Dalia; Yuan, Constance; Pavletic, Steven; Kanakry,
Jennifer A.; Ali, Syed Abbas; Mikkilineni, Lekha; Feldman, Steven A.;
Stroncek, David F.; Hansen, Brenna G.; Lawrence, Judith; Patel,
Rashmika; Hakim, Frances; Gress, Ronald E.; Kochenderfer, James N. |
Journal Of Clinical Oncology |
2018 |
| 38172 |
10.3324/haematol.2018.194118 |
Daratumumab Plus Bortezomib And Dexamethasone Versus
Bortezomib And Dexamethasone In Relapsed Or Refractory Multiple Myeloma:
Updated Analysis Of Castor |
Spencer, Andrew; Lentzsch, Suzanne; Weisel, Katja;
Avet-Loiseau, Herve; Mark, Tomer M.; Spicka, Ivan; Masszi, Tamas; Lauri,
Birgitta; Levin, Mark-David; Bosi, Alberto; Hungria, Vania; Cavo,
Michele; Lee, Je-Jung; Nooka, Ajay K.; Quach, Hang; Lee, Cindy; Barreto,
Wolney; Corradini, Paolo; Min, Chang-Ki; Scott, Emma C.; Chanan-Khan,
Asher A.; Horvath, Noemi; Capra, Marcelo; Beksac, Meral; Ovilla,
Roberto; Jo, Jae-Cheol; Shin, Ho-Jin; Sonneveld, Pieter; Soong, David;
Casneuf, Tineke; Chiu, Christopher; Amin, Himal; Qi, Ming; Thiyagarajah,
Piruntha; Sasser, A. Kate; Schecter, Jordan M.; Mateos,
Maria-Victoria |
Haematologica |
2018 |
| 38173 |
10.3324/haematol.2018.194282 |
Daratumumab Plus Lenalidomide And Dexamethasone Versus
Lenalidomide And Dexamethasone In Relapsed Or Refractory Multiple
Myeloma: Updated Analysis Of Pollux |
Dimopoulos, Meletios A.; San-Miguel, Jesus; Belch,
Andrew; White, Darrell; Benboubker, Lotfi; Cook, Gordon; Leiba, Merav;
Morton, James; Ho, P. Joy; Kim, Kihyun; Takezako, Naoki; Moreau,
Philippe; Kaufman, Jonathan L.; Sutherland, Heather J.; Lalancette,
Marc; Magen, Hila; Iida, Shinsuke; Kim, Jin Seok; Prince, H. Miles;
Cochrane, Tara; Oriol, Albert; Bahlis, Nizar J.; Chari, Ajai; O’Rourke,
Lisa; Wu, Kaida; Schecter, Jordan M.; Casneuf, Tineke; Chiu,
Christopher; Soong, David; Sasser, A. Kate; Khokhar, Nushmia Z.;
Avet-Loiseau, Herve; Usmani, Saad Z. |
Haematologica |
2018 |
| 38176 |
10.3324/haematol.2019.229781 |
Management Of Adults And Children Undergoing Chimeric
Antigen Receptor T-Cell Therapy: Best Practice Recommendations Of The
European Society For Blood And Marrow Transplantation (Ebmt) And The
Joint Accreditation Committee Of Isct And Ebmt (Jacie) |
Yakoub-Agha, Ibrahim; Chabannon, Christian; Bader,
Peter; Basak, Grzegorz W.; Bonig, Halvard; Ciceri, Fabio; Corbacioglu,
Selim; Duarte, Rafael F.; Einsele, Hermann; Hudecek, Michael; Kersten,
Marie Jose; Kohl, Ulrike; Kuball, Jurgen; Mielke, Stephan; Mohty,
Mohamad; Murray, John; Nagler, Arnon; Robinson, Stephen; Saccardi,
Riccardo; Sanchez-Guijo, Fermin; Snowden, John A.; Srour, Micha;
Styczynski, Jan; Urbano-Ispizua, Alvaro; Hayden, Patrick J.; Kroger,
Nicolaus |
Haematologica |
2019 |